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C-reactive protein (CRP) by nephelometry (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps doctors identify and monitor inflammation, often used to check for infections, autoimmune conditions, or other inflammatory diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100122-1
Short code
C pneum Ab Pnl Ser
Synonyms
C pneum Ab Pnl Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why CRP is Tested

Doctors may order CRP tests to evaluate symptoms like fever, joint pain, or unexplained swelling. It’s also used to monitor chronic conditions like rheumatoid arthritis or heart disease. Some tests are done as part of routine check-ups to detect early signs of inflammation.

How the Test Works

Your blood sample is taken and analyzed using a nephelometric method, which detects the amount of CRP in your serum or plasma. This test provides a quick result to help track inflammation levels over time.

What to Expect Before the Test

No special preparation is needed for this test. You can eat, drink, or take medications as usual on the day of your visit. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

Higher CRP levels often indicate inflammation, which could be caused by infections, injuries, or certain diseases. Lower levels suggest minimal inflammation. Your doctor will interpret the results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CRP is a useful marker for diagnosing and managing inflammatory conditions. Elevated levels may signal infections (like pneumonia or sepsis), autoimmune diseases (like lupus or vasculitis), or other inflammatory processes. It’s also used to assess the risk of heart disease and monitor treatment effectiveness in chronic conditions.

Short name

CRP

Frequently asked questions

How often should I get a CRP test?
The frequency depends on your health condition. Some people get CRP tests every few months to monitor chronic inflammation, while others may need them only if symptoms arise or as part of a routine check-up.
What are typical CRP reference ranges?
Reference ranges vary by lab and individual health. Low CRP levels (often below 1 mg/L) suggest minimal inflammation, while higher levels (above 10 mg/L) may indicate severe inflammation. Your doctor will provide your specific results and explain what they mean for you.
Can diet or exercise affect CRP levels?
Yes, lifestyle factors like diet, exercise, and stress can influence CRP levels. Eating a balanced diet rich in anti-inflammatory foods, staying active, and managing stress may help lower CRP levels over time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy