Skip to content

Pneumococcal Nucleic Acid Detection (Serum/Plasma Probe)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from *Streptococcus pneumoniae* (pneumococcus) in your blood or plasma, helping identify if this bacteria is present in your bloodstream.

Quick summary

["Assists in diagnosing pneumococcal infections, such as bacteremia, quickly and without culturing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88718-2
Short code
C pneum DNA Nph Ql NAA+probe
Synonyms
C pneum DNA Nph Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a specialized probe to detect genetic fragments (nucleic acid) from *Streptococcus pneumoniae*. This method is highly sensitive and can identify the bacteria even if it’s present in small amounts in your blood or plasma.

Why It’s Performed

Your healthcare provider may order this test if you have symptoms of a serious infection, such as fever, chills, or confusion, and suspect pneumococcal bacteria could be causing bloodstream infection (bacteremia) or pneumonia.

How the Test Works

A small blood sample is taken, and the genetic material is extracted. The probe then binds to any matching genetic sequences from *Streptococcus pneumoniae*, signaling a positive result if the bacteria is present.

When Results May Be Needed

Results are typically available within hours. A positive result indicates the presence of pneumococcal DNA, which may require immediate medical evaluation and treatment with antibiotics targeting pneumococcus.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pneumococcal DNA Probe

Frequently asked questions

How long does it take to get results?
Results are usually available within 4 to 8 hours, depending on lab processing times. Your doctor will discuss the results with you during your follow-up visit.
What does a positive result mean?
A positive result means genetic material from *Streptococcus pneumoniae* was detected in your blood or plasma. This suggests the bacteria may be causing an infection, and you’ll need further medical evaluation to determine the best treatment plan.
Can I eat or drink before the test?
You can eat and drink normally before the test, as it involves a simple blood draw. However, always follow your healthcare provider’s specific instructions for your procedure.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy