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Pneumococcal Nucleic Acid Detection in Respiratory Specimen (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic material from *Streptococcus pneumoniae* (pneumococcus) bacteria in your respiratory secretions, such as sputum or nasal swabs.

Quick summary

["Quickly identifies possible pneumococcal infection without waiting for culture results."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105884-1
Short code
C pneum DNA Spec Ql
Synonyms
C pneum DNA Spec Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fever, cough, difficulty breathing, or chest pain—especially if you’re at higher risk for pneumonia, such as young children, older adults, or those with weakened immune systems.

How the Test Works

A small sample of your respiratory secretions (e.g., sputum or nasal swab) is collected and analyzed using a molecular method to detect genetic material from pneumococcus. Results are typically available within hours.

Sample Collection

You’ll likely have a nasal swab or cough into a container. Avoid eating, drinking, or smoking for 15–30 minutes before testing to ensure accurate results.

What to Expect After the Test

No special preparation is needed beyond the timing mentioned above. Results are usually reported as ‘positive’ (pneumococcus detected) or ‘negative’ (no detectable bacteria).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test helps confirm a pneumococcal infection quickly, allowing for prompt treatment with antibiotics if needed. It’s particularly useful for ruling out other causes of respiratory illness, especially in high-risk patients.

Short name

Pneumococcal NAAT

Frequently asked questions

What does a positive result mean?
A positive result indicates that genetic material from *Streptococcus pneumoniae* was found in your sample. This suggests you may have an active pneumococcal infection and should follow your provider’s advice for treatment, which may include antibiotics.
Can this test be used for other infections?
No, this test specifically detects *Streptococcus pneumoniae* bacteria. Other infections (e.g., viral or bacterial like *Streptococcus pyogenes*) would require different tests.
How soon will I get my results?
Results are typically available within 2–4 hours, depending on lab processing times. Your provider will discuss them with you during your follow-up visit.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy