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Pneumococcal Nucleic Acid Detection (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from *Streptococcus pneumoniae* (pneumococcus) bacteria in your blood or plasma, which may indicate an infection.

Quick summary

["Helps diagnose serious bacterial pneumonia or bloodstream infections quickly."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107363-4
Short code
C pneum DNA Spt Ql NAA+n-prb
Synonyms
C pneum DNA Spt Ql NAA+n-prb
Category
chemistry
Sample
sputum
Container
Sterile sputum container
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
CPT
85610
SNOMED
396252006
Specimen volume
3-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
TAT
4–24 hours
Order
routine

Why This Test Matters

Pneumococcal bacteria can cause severe infections like pneumonia, meningitis, or sepsis. Detecting their genetic material early can guide faster treatment decisions, especially in high-risk groups like the elderly or those with weakened immune systems.

What to Expect Before the Test

No special preparation is needed. A blood sample will be drawn from a vein, similar to other blood tests. The sample is processed to detect pneumococcal DNA using advanced molecular techniques.

What the Results Mean

A positive result means the test identified genetic material from pneumococcus. This suggests an active infection, prompting urgent medical evaluation. A negative result means no detectable genetic material was found in this sample.

When You Might Need This Test

Your doctor may order this test if you have symptoms like high fever, difficulty breathing, or rapid heartbeat, especially if you’ve been exposed to pneumococcal bacteria or have a known infection risk.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: sputum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Pneumococcal DNA Test

Frequently asked questions

When could I get my results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your doctor will contact you directly with the results.
Is this test covered by insurance?
Most insurance plans cover this test if ordered by a doctor for diagnosing serious infections. Check with your insurance provider for specifics, as coverage may vary.
What if I have a mild cold or flu-like symptoms?
This test is not typically used for routine colds or viral infections. It’s reserved for suspected pneumococcal bacterial infections, especially in severe or high-risk cases.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy