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C-reactive protein (CRP) in serum/plasma by nephelometry (high-sensitivity)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by the liver in response to inflammation, helping doctors assess your risk for certain health conditions.

Quick summary

["Helps track inflammation and cardiovascular risk over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92577-6
Short code
C pneum DNA Upper resp Ql NAA+probe
Synonyms
C pneum DNA Upper resp Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to monitor chronic conditions like arthritis, heart disease, or infections. It can also help evaluate whether inflammation is present in your body, even if you don’t have obvious symptoms.

What Does the Test Measure?

The test measures the concentration of C-reactive protein (CRP) in your blood. CRP is a marker that rises when your body is fighting inflammation, often due to infections, injuries, or autoimmune diseases.

How Is the Sample Collected?

A small blood sample is drawn from a vein, usually in your arm. The blood is then sent to a lab for analysis.

What Are Common Uses?

High-sensitivity CRP is often used to assess long-term risk for heart disease, monitor inflammatory conditions like rheumatoid arthritis, or evaluate responses to treatments that target inflammation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

High-sensitivity CRP (hs-CRP)

Frequently asked questions

What does a high or low CRP level mean?
A high CRP level suggests increased inflammation, which could be due to infections, injuries, or certain medical conditions. A low level typically means less inflammation is present, but it doesn’t rule out other possible causes. Your doctor will interpret results in the context of your overall health and symptoms.
How often should I get this test?
Your doctor will determine how often you need this test based on your medical history, current health status, and treatment plan. Some people may need it yearly, while others may need it more or less frequently.
Can lifestyle changes affect CRP levels?
Yes, lifestyle factors like diet, exercise, smoking, and stress can influence CRP levels. Eating a heart-healthy diet, staying active, and avoiding smoking may help lower CRP levels over time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy