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Pneumococcal Group Antigen in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against *Streptococcus pneumoniae* (pneumococcus) in your blood. These antibodies help your immune system recognize and fight off this common bacterial cause of pneumonia, meningitis, and other infections.

Quick summary

["Helps identify if your body has developed immunity against pneumococcal bacteria, useful before vaccination or in monitoring immune response."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
31300-7
Short code
C pneum IgA Ser-aCnc
Synonyms
C pneum IgA Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’re at higher risk for pneumococcal infections—such as people with weakened immune systems, those with chronic health conditions (like heart or lung disease), or those who’ve recently received a pneumococcal vaccine. It may also be used to assess immune response after vaccination.

How the Test Works

Blood is drawn and analyzed to detect specific antibodies (antigens) produced by your immune system in response to pneumococcal bacteria. The test measures these antibodies in your serum, often using a sensitive immunoassay method to detect even small amounts.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood, which usually takes a few minutes. If you’re on blood thinners or have a history of bleeding issues, let your provider know.

What the Results Mean

Results are qualitative (positive or negative) and indicate whether antibodies against pneumococcal are present. A positive result suggests your immune system has recognized the bacteria, while a negative result means no detectable antibodies were found.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Pneumococcal Antibody Screening

Frequently asked questions

How does this test help doctors?
This test helps determine if you have developed immunity against pneumococcal bacteria, which is critical for guiding vaccination decisions, monitoring immune function in high-risk patients, or evaluating the effectiveness of preventive measures.
What if my results are positive?
A positive result means your immune system has likely encountered pneumococcal bacteria before, which may protect you from future infections. However, it doesn’t replace vaccination—vaccines are still recommended for prevention.
Could this test be affected by recent illness?
Yes, recent infections or exposure to pneumococcal bacteria could temporarily increase antibody levels. If you’ve had recent symptoms or exposure, your provider may wait to retest or adjust interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy