C-reactive protein, serum (high-sensitivity)
This test measures a protein in your blood that rises when inflammation is present, often used to check for signs of infection, injury, or other inflammatory conditions.
["hs-CRP helps track inflammation, aiding in early detection of conditions like heart disease or autoimmune disorders."]
Key facts at a glance
- LOINC
- 110993-3
- Short code
- C pneum IgG Msmt Ser
- Synonyms
- C pneum IgG Msmt Ser
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your doctor may order this test to monitor chronic conditions like heart disease, arthritis, or to check for signs of infection, injury, or other inflammatory processes after surgery or trauma. It can also help assess how well treatments for inflammation are working.
What Does a High or Low Result Mean?
Elevated levels may indicate inflammation, infections, or conditions like rheumatoid arthritis or heart disease. Lower-than-normal results might suggest reduced inflammation, but they don’t always mean you’re healthy. Results depend on your overall health and medical history.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The blood is sent to a lab where it’s processed to separate serum. The test measures the protein using a sensitive method to detect even small amounts of inflammation.
What Are Common Causes of Abnormal Results?
High hs-CRP levels can be caused by infections, autoimmune diseases, heart problems, or recent injuries. Low levels may occur if inflammation is minimal, but they don’t rule out underlying issues. Other factors like age, diet, and medications can also affect results.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: hs-CRP plays a key role in assessing long-term inflammation risk, guiding preventive care, and evaluating treatment responses in chronic diseases. It’s not a diagnostic test for specific conditions but helps monitor broader health trends.
Short name
hs-CRP
Frequently asked questions
What does a high hs-CRP level mean for my health?
Can lifestyle changes affect hs-CRP levels?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy