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Neutrophil count in cerebrospinal fluid (CSF) via quantitative turbidimetric assay

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of neutrophils, a type of white blood cell, in your cerebrospinal fluid (CSF). It helps assess conditions affecting the brain and spinal cord, such as infections or inflammation.

Quick summary

["Neutrophils in CSF can signal serious neurological issues that require prompt medical attention."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
21184-7
Short code
C pneum Spec Ql Cult
Synonyms
C pneum Spec Ql Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like severe headaches, neck stiffness, fever, confusion, or neurological problems. It’s often used to diagnose conditions such as meningitis, brain infections, or other inflammatory diseases in the central nervous system.

What to Expect During the Test

A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). You’ll lie on your side, and a needle is gently inserted into your lower back to draw the fluid. The process is usually quick and may cause mild discomfort.

How the Results Are Interpreted

Elevated neutrophil counts in CSF often indicate an infection (e.g., bacterial meningitis) or severe inflammation. Lower-than-expected counts may suggest conditions like multiple sclerosis or other non-infectious causes. Your doctor will review the results in the context of your symptoms and medical history.

Common Conditions This Test Helps Diagnose

This test is critical for diagnosing infections like bacterial meningitis, abscesses in the brain or spinal cord, or conditions causing inflammation (e.g., acute disseminated encephalomyelitis). It can also help rule out other neurological disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CSF Neutrophil Count

Frequently asked questions

What does a high neutrophil count in CSF mean?
A high neutrophil count in CSF is most commonly associated with bacterial infections (e.g., bacterial meningitis) or severe inflammatory processes. Your doctor will guide you on next steps, which may include antibiotics or additional tests.
How is CSF collected for this test?
CSF is collected through a procedure called a lumbar puncture, where a needle is inserted into your lower back to draw fluid from your spinal canal. It’s a quick but may cause mild discomfort.
Can lifestyle changes affect neutrophil counts in CSF?
Neutrophil counts in CSF are primarily influenced by infections, inflammation, or underlying neurological conditions. Lifestyle factors like diet or stress do not directly impact this test result, but they can influence overall health and symptom severity.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy