Neutrophil count in cerebrospinal fluid (CSF) via quantitative turbidimetric assay
This test measures the number of neutrophils, a type of white blood cell, in your cerebrospinal fluid (CSF). It helps assess conditions affecting the brain and spinal cord, such as infections or inflammation.
["Neutrophils in CSF can signal serious neurological issues that require prompt medical attention."]
Key facts at a glance
- LOINC
- 21184-7
- Short code
- C pneum Spec Ql Cult
- Synonyms
- C pneum Spec Ql Cult
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- organism-specific-culture
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have symptoms like severe headaches, neck stiffness, fever, confusion, or neurological problems. It’s often used to diagnose conditions such as meningitis, brain infections, or other inflammatory diseases in the central nervous system.
What to Expect During the Test
A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). You’ll lie on your side, and a needle is gently inserted into your lower back to draw the fluid. The process is usually quick and may cause mild discomfort.
How the Results Are Interpreted
Elevated neutrophil counts in CSF often indicate an infection (e.g., bacterial meningitis) or severe inflammation. Lower-than-expected counts may suggest conditions like multiple sclerosis or other non-infectious causes. Your doctor will review the results in the context of your symptoms and medical history.
Common Conditions This Test Helps Diagnose
This test is critical for diagnosing infections like bacterial meningitis, abscesses in the brain or spinal cord, or conditions causing inflammation (e.g., acute disseminated encephalomyelitis). It can also help rule out other neurological disorders.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
CSF Neutrophil Count
Frequently asked questions
What does a high neutrophil count in CSF mean?
How is CSF collected for this test?
Can lifestyle changes affect neutrophil counts in CSF?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy