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Upper Respiratory Tract Pathogen Detection by Probe (Multiplex PCR)

Published: August 9, 2026Updated: August 16, 2026

This test checks for common viruses and bacteria that may cause infections in your upper respiratory system, such as the throat or sinuses.

Quick summary

["Helps identify possible causes of colds, sinus infections, or other respiratory illnesses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92860-6
Short code
C pn + M pn DNA Pnl Upper resp NAA+probe
Synonyms
C pn + M pn DNA Pnl Upper resp NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test uses a specialized probe to detect genetic material (DNA/RNA) from specific pathogens, including viruses like rhinovirus, coronavirus, influenza, and respiratory syncytial virus (RSV), as well as bacteria like Streptococcus pneumoniae or Haemophilus influenzae. It’s designed to quickly identify potential causes of respiratory symptoms.

How the Test Works

A small sample of your nasal or throat swab is collected and analyzed in a laboratory. The test uses polymerase chain reaction (PCR) technology to amplify and identify genetic material from targeted pathogens, providing results in a few hours or days depending on lab processing.

When You Might Need This Test

Your healthcare provider may recommend this test if you have symptoms like coughing, sore throat, runny nose, or difficulty breathing, especially if you’re experiencing severe or persistent symptoms that don’t improve with over-the-counter medications.

Common Symptoms to Watch For

Symptoms such as fever, headache, fatigue, or worsening congestion could indicate an infection that this test can help diagnose. It’s particularly useful for children, older adults, or those with weakened immune systems.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Upper Resp Probe

Frequently asked questions

Why is this test important?
This test helps narrow down the cause of your symptoms, allowing your doctor to choose the most effective treatment. Accurate identification of the pathogen can prevent unnecessary antibiotics if the cause is viral, reduce exposure risks, and improve recovery time.
How soon can I expect results?
Results are typically available within 24 to 48 hours, depending on lab workflow and processing times. Your healthcare provider will discuss the findings with you during your follow-up visit.
What if my test comes back positive?
If the test detects a pathogen, your doctor may recommend specific treatments like antiviral medications, supportive care, or monitoring. Follow their guidance closely to manage symptoms and prevent complications.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy