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C-reactive protein (CRP) by nephelometry

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify inflammation, often used to monitor conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
46776-1
Short code
CPT2/CACT DBS-Imp
Synonyms
CPT2/CACT DBS-Imp
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a CRP test to check for signs of inflammation, monitor chronic conditions like rheumatoid arthritis or lupus, or evaluate symptoms such as fever, joint pain, or unexplained fatigue. It can also help assess the risk of heart disease or guide treatment decisions for infections.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample. If you’re on blood thinners, let your doctor know before the test.

What the Results Mean

CRP levels vary depending on your health and condition. Higher levels may indicate inflammation, while lower levels suggest minimal or no inflammation. Your doctor will interpret results in the context of your medical history and other tests.

Common Conditions Monitored

CRP is often used to track conditions like infections (e.g., pneumonia, urinary tract infections), autoimmune diseases (e.g., lupus, rheumatoid arthritis), or to assess cardiovascular risk. It can also help monitor responses to treatments.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP serves as a general marker for inflammation. While not specific to a single condition, elevated CRP can signal underlying inflammation that may require further investigation, such as additional tests or medical evaluation.

Short name

CRP

Frequently asked questions

What causes CRP levels to change?
CRP levels can rise due to infections, injuries, surgeries, or certain medications. They may also fluctuate with chronic conditions like arthritis or heart disease. Stress, smoking, or poor diet can temporarily affect CRP levels.
How often should I get this test?
Your doctor will determine the frequency based on your health needs. Some people get CRP tests yearly or more often if they have ongoing conditions like heart disease or autoimmune disorders.
Can diet or lifestyle affect CRP levels?
Yes, diet, exercise, and weight management can influence CRP levels. Reducing inflammation through a heart-healthy diet, quitting smoking, and managing stress may help lower CRP levels over time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy