This page explains the Hemoglobin A1c (HbA1c) test, also known as the glycated hemoglobin test, which is commonly used to monitor long-term blood sugar control in people with diabetes, and also helps diagnose prediabetes and diabetes.
This test measures the amount of creatinine in a urine sample collected over 18 hours to assess kidney function.
{"Creatinine is a waste product from muscle metabolism filtered by kidneys","This test helps evaluate how well your kidneys are working","You will need to collect all urine produced over an 18-hour period","Results help diagnose and monitor kidney disease","Proper sample collection is crucial for accurate results"}
Key facts at a glance
- LOINC
- 58998-6
- Short code
- UCR18
- Synonyms
- Creat 18h Ur-mRate
- Category
- kidney
- Sample
- urine
- Container
- 24-hour urine collection container with preservative (optional)
- Units
- not specified
- Ref low
- 750
- Ref high
- 1500
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 18 years
- Method
- Enzymatic or Jaffe kinetic colorimetric assay
- CPT
- 82570
- SNOMED
- 271344006
- Specimen volume
- Complete 18-hour collection, typically 800-2000 mL depending on urine output
- Stability
- Room temperature: 24-48 hours; Refrigerated (2-8°C): 5-7 days; Frozen (-20°C): 30 days
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 24–72 hours
- Order
- routine
This test measures the average amount of sugar (glucose) in your blood over the past two to three months by checking how much glucose has attached to hemoglobin, the oxygen-carrying protein in your red blood cells, giving a clear picture of your long-term blood sugar levels.
The 18-hour urine creatinine test measures how much creatinine is eliminated from your body through urine over an 18-hour period. Creatinine is a waste product created when muscles break down creatine, a substance used for muscle energy. Healthy kidneys filter creatinine from the blood and excrete it in urine.
Your doctor orders this test to check for prediabetes or diabetes, to monitor how well you are managing existing diabetes, to adjust your current treatment plan if needed, and to identify your risk of developing complications like heart disease, kidney damage, or nerve problems.
This test is primarily used to evaluate kidney function and detect kidney disease. It helps doctors assess how well your kidneys are filtering waste from your blood. The test may also be used to monitor kidney function in patients with known kidney disease or those taking medications that may affect kidney function.
No special preparation like fasting or dietary changes is needed for this test, and you can eat and drink normally beforehand; a blood sample is drawn from a vein in your arm or via a fingerstick, but inform your doctor about any vitamins, supplements, or medications you take.
Your healthcare provider will give you specific instructions. Generally, you will receive a special container for urine collection. On the collection day, start by urinating at a specific time (usually morning) and discard this first sample. Then collect all subsequent urine for the next 18 hours, including the first morning urine on the second day. Keep the container refrigerated or in a cool place during collection. Label the container with your name, date, and collection times.
Results are given as a percentage, with a normal reading below 5.7%, prediabetes in the range of 5.7% to 6.4%, and diabetes at 6.5% or higher, and your doctor will explain what your specific number means and discuss appropriate steps.
Normal creatinine excretion varies based on factors like muscle mass, age, sex, and diet. Higher than normal creatinine levels in urine may indicate kidney problems, while lower levels could suggest reduced kidney function or other conditions. Your doctor will interpret your results based on your individual health profile.
Reference range
750-1500 mg/18 hr (varies by gender/muscle mass)not specified
Complete timed 18-hour urine collection; refrigerate during collection; no fasting required
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
The 18-hour urine creatinine test is valuable for assessing renal function and detecting early kidney damage. It helps in the diagnosis of chronic kidney disease, acute kidney injury, and conditions affecting kidney filtration. The test is also useful for monitoring disease progression and evaluating the effectiveness of treatment. Additionally, it can help distinguish between different types of kidney disorders and assess overall kidney filtration capacity.
Frequently asked questions
Do I need to fast before this test?
What happens if I miss a urine collection during the 18-hour period?
Are there any risks associated with this test?
How long does it take to get results?
Can I exercise before or during the collection period?
Sources
- 1
- 2
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy