Understanding the A1C Test: A Comprehensive Guide to Blood Sugar Control and Diabetes Monitoring for Patients
A test that measures the amount of creatinine in urine collected over 24 hours to evaluate kidney function.
{"Measures how much creatinine your kidneys filter out in a day","Helps assess kidney function and detect kidney disease","Requires collecting all urine for 24 hours","Results are compared with blood creatinine levels","Accurate assessment of kidney filtration ability"}
Key facts at a glance
- LOINC
- 40357-6
- Short code
- CR24H
- Synonyms
- Creat 24h Fld-sRate
- Category
- kidney
- Sample
- serum
- Container
- 24-hour urine collection container, typically with preservative (e.g., hydrochloric acid or boric acid)
- Units
- not specified
- Ref low
- 5.8
- Ref high
- 13.3
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- ≥ 18 years
- Method
- Enzymatic or Jaffe colorimetric assay
- CPT
- 82520
- SNOMED
- 39854008
- Specimen volume
- Complete 24-hour urine collection, typically 1000-2000 mL total volume
- Stability
- Refrigerated: 7 days; Frozen at -20°C: 30 days; Protect from light
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 24–72 hours
- Order
- routine
The A1C test, also known as the glycated hemoglobin test, measures the average amount of sugar (glucose) attached to hemoglobin in your red blood cells over the past two to three months. This provides a longer-term picture of your blood sugar control, unlike a regular blood sugar check which only shows your level at a single moment. The test is a vital tool for diagnosing prediabetes and diabetes, and for tracking how well your current diabetes management plan is working. It is a simple and reliable way to see if your blood sugar has been consistently within a healthy range, and it helps you and your healthcare provider make informed decisions about your diet, exercise, and medication. The result is reported as a percentage, and a higher percentage means higher average blood sugar levels. For most people with diabetes, the goal is to stay below 7%, but your individual target may vary based on your health history and other factors.
The 24-hour urine creatinine test measures the amount of creatinine excreted in your urine over a 24-hour period. Creatinine is a waste product produced by normal muscle metabolism and is filtered out of the blood by healthy kidneys. This test helps doctors evaluate how well your kidneys are functioning.
The A1C test is performed by drawing a small sample of blood from a vein in your arm, usually from the inside of the elbow. A healthcare professional will clean the area with an antiseptic wipe, place a tourniquet around your upper arm to make the vein more visible, and then insert a thin needle to collect the blood into a vial. The procedure typically takes just a few minutes and is considered low-risk. You do not need to fast or make any special preparations before this test, and you can eat and drink normally. The blood sample is then sent to a laboratory for analysis, and the results are usually available within a few days. The test is safe for most people, although you may feel a slight sting when the needle is inserted, and there is a small chance of bruising or soreness at the puncture site. Some clinics offer a point-of-care test using a fingerstick that gives results in about five minutes, but the standard laboratory method is the most accurate.
You will receive a special container for urine collection. On the first day, you will urinate into the container after the first morning void and save all urine for the next 24 hours. The next morning, you will collect the first morning urine and add it to the container. Keep the container refrigerated during the collection period. Return the complete collection to the laboratory as instructed.
The A1C test is essential because it provides a comprehensive view of your blood sugar management over time, which is crucial for preventing the serious complications of diabetes. Consistently high blood sugar levels can damage your blood vessels, nerves, and organs, leading to heart disease, kidney failure, vision loss, and other health problems. By measuring your A1C regularly, you can catch these risks early and adjust your lifestyle or medications to keep your blood sugar in a healthy range. For people without diabetes, this test helps identify prediabetes, a condition where blood sugar is higher than normal but not yet diabetes, allowing for early intervention through weight loss, diet changes, and increased physical activity. Regular A1C testing is recommended for anyone over 45, or earlier if you have risk factors like obesity or a family history of diabetes. With proper management, you can significantly reduce your risk of complications and live a longer, healthier life. The test empowers you and your doctor to make proactive choices that protect your long-term health.
This test is crucial for assessing kidney function because creatinine is produced at a relatively constant rate by the body. By measuring how much creatinine is eliminated in the urine over 24 hours, doctors can calculate creatinine clearance, which estimates the glomerular filtration rate (GFR) - a key indicator of kidney function.
Reference range
7.1-17.7 mmol/24h (sex- and muscle mass-dependent; males typically 8.8-17.7, females 7.1-15.9)not specified
Complete 24-hour collection of body fluid (typically urine); discard first void, collect all subsequent including next morning void. No fasting required; avoid strenuous exercise.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
Do I need to fast before the test?
What happens if I miss a urine sample during collection?
Can women have this test during menstruation?
How long does it take to get results?
Sources
- 1
- 2
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy