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Creat24hurmcnc

Published: July 31, 2026Updated: August 16, 2026

A test that measures the amount of creatinine in your urine over a 24-hour period to assess kidney function.

Quick summary

{"Creatinine is a waste product filtered from blood by kidneys","24-hour collection provides a more accurate assessment than a single urine sample","Results help evaluate kidney function and detect kidney disease","The test measures how much creatinine your kidneys filter and excrete","It can also help estimate your muscle mass"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
20624-3
Short code
CRU24
Synonyms
Creat 24h Ur-mCnc
Category
kidney
Sample
urine
Container
24-hour urine collection container with or without preservative (toluene or thymol)
Units
not specified
Ref low
20
Ref high
300
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Spectrophotometric (Jaffe reaction or enzymatic method)
CPT
82570
SNOMED
271717005
Specimen volume
Complete 24-hour urine collection (typically 1000-2000 mL, record exact volume)
Stability
Refrigerated (2-8°C): up to 7 days; Room temperature (15-25°C): up to 3 days; Frozen (-20°C): up to 30 days
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
24–48 hours
Order
routine

What is this test?

The 24-hour urine creatinine test measures the amount of creatinine in your urine over a 24-hour period. Creatinine is a waste product produced by your muscles during normal muscle breakdown. Your kidneys filter creatinine from your blood and excrete it in urine. This test helps doctors evaluate how well your kidneys are functioning.

How is the test performed?

You will receive a special container for collecting all urine over 24 hours. Start by urinating into the toilet when you wake up, then note the time. For the next 24 hours, collect all urine in the provided container. Keep the container refrigerated or in a cool place. At the end of 24 hours, urinate one last time and add this to the container. Return the container to your healthcare provider as instructed.

What do the results mean?

Normal creatinine clearance varies based on age, gender, and muscle mass. Higher than expected creatinine in urine generally indicates good kidney function, while lower levels may suggest kidney problems. Your doctor will interpret your results based on your individual situation, including other blood and urine tests.

Reference range

20-300 mg/dLnot specified

Specimen: urine

Complete 24-hour urine collection required (discard first morning void; collect all urine for next 24 h including next morning void). No fasting needed. Avoid strenuous exercise and high meat intake during collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Does diet affect urine creatinine levels?
Yes, diet can affect creatinine levels. Eating large amounts of cooked meat can temporarily increase creatinine. Staying well-hydrated helps ensure accurate results. Your doctor may advise you to avoid certain foods or supplements before the test.
Should I avoid exercise before the test?
Avoid strenuous exercise for 24-48 hours before and during the collection period, as intense exercise can increase muscle metabolism and temporarily raise creatinine levels.
What happens if I miss a urine sample during collection?
If you miss collecting a sample, note the time and continue with the collection. Try to collect all urine for the full 24 hours. Contact your healthcare provider if you have concerns about incomplete collection.
Are there any risks to this test?
There are no medical risks to this test. The main challenge is accurately collecting all urine over the 24-hour period. Follow the collection instructions carefully for accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy