Skip to content

Creat24hurscnc

Published: July 31, 2026Updated: August 16, 2026

A test that measures the amount of creatinine in your urine over a 24-hour period to evaluate kidney function.

Quick summary

{"Creatinine is a waste product from muscle metabolism filtered by kidneys","This test helps assess how well your kidneys are working","You will need to collect all urine in a special container for 24 hours","Results are often compared with blood creatinine levels","Abnormal results may indicate kidney disease or muscle disorders"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25886-3
Short code
U_CREAT_24H
Synonyms
Creat 24h Ur-sCnc
Category
kidney
Sample
urine
Container
Sterile graduated urine collection container (24-hour)
Units
not specified
Ref low
8.4
Ref high
13.6
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Jaffe colorimetric reaction (creatinine picrate method) or enzymatic method
CPT
82570
SNOMED
271258001
Specimen volume
Complete 24-hour collection (typically 1000-3000 mL, volume must be measured and recorded)
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 7 days; Frozen (-20°C): 30 days
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
24–72 hours
Order
routine

What is this test?

The 24-hour urine creatinine test measures how much creatinine your kidneys filter out of your blood and excrete in urine over a 24-hour period. Creatinine is a waste product produced naturally by your muscles as part of normal daily activity. Healthy kidneys filter creatinine from your blood and eliminate it through urine.

How to collect the sample

For this test, you will need to collect all urine you produce over a 24-hour period. Your healthcare provider will give you a special container. On the morning of the collection day, start by urinating into the toilet (not the container). After that, every time you urinate for the next 24 hours, collect the urine in the container. Keep the container refrigerated or in a cool place. Return the complete collection to your laboratory as instructed.

What do the results mean?

Normal creatinine levels in urine vary based on factors like age, sex, and muscle mass. Higher than normal urine creatinine may indicate conditions that increase muscle breakdown. Lower than normal levels may suggest kidney problems, as the kidneys are not filtering creatinine properly. Your healthcare provider will interpret your results alongside other tests, such as blood creatinine and estimated glomerular filtration rate (eGFR).

Reference range

Male: 8.8-17.7 mmol/24 h; Female: 7.1-15.9 mmol/24 hnot specified

Specimen: urine

Complete 24-hour urine collection required (discard first morning void, collect all urine for next 24 hours including final morning void); no fasting needed but avoid excessive meat intake and strenuous exercise

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Do I need to fast before this test?
No fasting is usually required for a 24-hour urine creatinine test. However, avoid strenuous exercise during the collection period, as excessive muscle activity can temporarily increase creatinine levels. Follow any specific instructions from your healthcare provider.
Why do I need to collect urine for 24 hours?
A 24-hour collection provides a more accurate picture of kidney function than a single urine sample. Creatinine levels can vary throughout the day based on diet, activity, and hydration. The 24-hour collection averages out these variations, giving a more reliable assessment of how well your kidneys are working.
What happens if I miss a urine sample during collection?
If you forget to collect a sample or accidentally spill some urine, contact your healthcare provider or laboratory for guidance. They may advise you to restart the collection or continue with the partial sample. It is important to be as accurate as possible for reliable results.
Can medications affect the test results?
Yes, certain medications can affect creatinine levels. These include some antibiotics, diuretics, and drugs that affect kidney function. Inform your healthcare provider about all medications and supplements you are taking before the test.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy