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Creatvitfmcnc

Published: July 31, 2026Updated: August 16, 2026

A test that measures creatinine levels in the vitreous fluid of the eye to assess kidney function or help estimate time of death in forensic cases.

Quick summary

{"Measures creatinine in the eye's vitreous fluid","Used primarily in forensic medicine to estimate postmortem interval","Helps assess kidney function when blood/urine samples unavailable","Sample is collected from the eye after death","Results are compared with normal reference ranges"}

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12584-9
Short code
CREA-VITR
Synonyms
Creat Vitf-mCnc
Category
kidney
Sample
serum
Container
Sterile airtight container, preferably glass tube
Units
not specified
Ref low
0.5
Ref high
1.5
Critical range
— – 2.5 not specified
Fasting
false
Population
adult
Sex
all
Age range
≥ 18 years
Method
Enzymatic method or Jaffe kinetic reaction
CPT
82565
SNOMED
271563006
Specimen volume
0.5-1.0 mL of vitreous fluid
Stability
Room temperature: 24 hours; Refrigerated (2-8°C): 72 hours; Frozen (-20°C): several weeks
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
24–72 hours
Order
routine

What is this test?

The Vitreous Fluid Creatinine test measures the amount of creatinine, a waste product from muscle metabolism, in the vitreous fluid—the clear, gel-like substance that fills the eye between the lens and the retina. This test is primarily used in forensic pathology but may also provide information about kidney function in certain clinical situations.

How is the sample collected?

The sample is collected from the vitreous humor of the eye using a needle after death (in forensic cases) or in rare clinical situations where other bodily fluids cannot be obtained. The procedure is performed by a trained medical professional or pathologist.

What do the results mean?

Creatinine levels in vitreous fluid can indicate how well the kidneys were functioning before death. Elevated levels may suggest kidney dysfunction or reduced kidney function. In forensic medicine, analyzing vitreous fluid creatinine, along with other markers, can help estimate the approximate time of death.

Reference range

0.5-1.5 mg/dLnot specified

Specimen: serum

None; typically postmortem vitreous aspiration specimen

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

Is this test painful?
The vitreous fluid sample is collected after death, so the procedure does not cause pain to the patient. In living patients, this test is extremely rare and would require local anesthesia.
How long does it take to get results?
Results are typically available within 24-48 hours, depending on the laboratory processing the sample.
Do I need to fast before this test?
Since this test is primarily performed postmortem, fasting is not applicable. If performed in a living patient (which is very rare), your healthcare provider will give you specific instructions.
Can this test diagnose kidney disease?
This test is not a primary diagnostic tool for kidney disease in living patients. Blood tests (serum creatinine) and urine tests are the standard methods for diagnosing kidney conditions. Vitreous fluid creatinine is mainly used in forensic settings.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy