Skip to content

C-reactive protein (mass concentration) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps doctors assess inflammation, often used to monitor conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48421-2
Short code
CRP BldC-mCnc
Synonyms
CRP BldC-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
0
Ref high
3
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86140
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a CRP test to check for signs of inflammation. This can help diagnose conditions like infections (e.g., pneumonia), autoimmune diseases (e.g., rheumatoid arthritis), or to monitor healing after surgery or injury.

What Does a High CRP Level Mean?

Elevated CRP levels often indicate inflammation or infection. While not specific to one condition, it can signal areas needing further investigation, such as infections, injuries, or certain chronic diseases.

What Does a Low CRP Level Mean?

Low CRP levels usually mean there is little to no active inflammation in your body. However, very low levels might also suggest conditions like severe malnutrition or certain immune deficiencies.

How Is This Test Performed?

A small blood sample is taken from a vein, usually in your arm. The blood is then sent to a lab where it is analyzed to measure CRP levels using a sensitive detection method.

Reference range

Normal: <3.0 mg/LN/A

Specimen: whole-blood

No special preparation required. CRP may be affected by acute illness.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP is a non-specific marker of inflammation. It is commonly used as a screening tool to identify potential inflammatory processes, guide treatment decisions, or monitor disease activity in conditions like infections, autoimmune disorders, or cardiovascular risk assessment. While CRP does not pinpoint the exact cause of inflammation, it provides valuable context for further evaluation.

Short name

CRP (Serum/Plasma)

Frequently asked questions

What causes CRP levels to change?
CRP levels can rise due to infections (like colds or flu), injuries, surgeries, or certain medical conditions such as autoimmune diseases (e.g., lupus). They may also be influenced by factors like stress, smoking, or certain medications.
How long does it take to get results?
Results from a CRP test are typically available within 1 to 3 business days, depending on your lab’s processing time.
Can diet or lifestyle affect CRP levels?
Yes, diet and lifestyle can influence CRP levels. Reducing inflammation through a balanced diet, regular exercise, and avoiding smoking may help lower CRP levels over time.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy