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C-reactive protein (mass concentration) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps doctors assess inflammation, often used to monitor conditions like infections, autoimmune diseases, or after surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
16503-5
Short code
CRP Fld-mCnc
Synonyms
CRP Fld-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
3
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86140
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for signs of inflammation, monitor chronic conditions like rheumatoid arthritis or lupus, or evaluate your response to treatment. It can also help identify infections or other inflammatory processes in your body.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s drawn from a blood sample, but this depends on your lab’s protocol. Bring any medications or supplements you’re taking to your appointment.

How the Test Is Performed

A healthcare professional will draw blood from a vein in your arm using a small needle. The blood sample is then sent to a lab for analysis. The test measures CRP levels in your serum or plasma.

What the Results Mean

Higher CRP levels often indicate inflammation, which can be caused by infections, injuries, or autoimmune diseases. Lower levels suggest minimal inflammation. Your results will be compared to standard reference ranges provided by your lab.

Reference range

Normal: <3.0 mg/LN/A

Specimen: serum

No special preparation required. CRP may be affected by acute illness.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated CRP is a general marker of inflammation and can guide treatment decisions, such as adjusting medications for conditions like arthritis or monitoring healing after surgery. It’s not specific to one disease but helps track overall inflammatory activity in the body.

Short name

CRP (Serum/Plasma)

Frequently asked questions

What causes CRP levels to change?
CRP levels can rise due to infections (like pneumonia or urinary tract infections), injuries, surgeries, or autoimmune diseases (like rheumatoid arthritis). Stress, certain medications, or pregnancy may also temporarily affect CRP levels.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the results with you during your follow-up visit.
Can I eat or drink before this test?
Most labs recommend fasting for 8–12 hours before a CRP test if drawn from blood, but always follow your lab’s specific instructions to avoid potential interference with results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy