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C-reactive protein (mass concentration) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation or infection in your body.

Quick summary

["CRP helps doctors assess inflammation and identify possible infections or conditions like autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
8181-0
Short code
Cr Sal-mCnc
Synonyms
Cr Sal-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to monitor inflammation, check for infections, evaluate autoimmune conditions, or assess response to treatment for conditions like arthritis or heart disease. It can also be used to screen for certain risks, such as cardiovascular disease.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. If you’re taking blood from a finger, no fasting is required.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but it usually doesn’t cause significant discomfort. The blood sample is then sent to a lab for analysis.

What Are Possible Results?

Results are typically reported in milligrams per liter (mg/L). Higher than normal levels may indicate inflammation, infection, or other health issues. Your results will be discussed with your doctor to determine next steps.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP is a marker for inflammation. Elevated levels can signal infections (such as pneumonia or urinary tract infections), autoimmune diseases (like rheumatoid arthritis), or other inflammatory conditions. It’s also used to monitor treatment effectiveness or screen for risks like heart disease.

Short name

CRP (Serum/Plasma)

Frequently asked questions

What does a high CRP level mean?
A high CRP level suggests your body is actively fighting inflammation or infection. Your doctor may investigate further to identify the cause, such as an infection, autoimmune disease, or other underlying conditions.
Can diet or exercise affect CRP levels?
Yes, lifestyle factors like diet, exercise, and stress can influence CRP levels. Eating a balanced diet, staying active, and managing stress may help lower inflammation over time.
Is CRP the same as a white blood cell count?
No, CRP measures a specific protein linked to inflammation, while a white blood cell count assesses the number of immune cells in your blood. Both tests provide different insights into health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy