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C-reactive protein (CRP) mass concentration in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify inflammation, often used to monitor conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
20759-7
Short code
Cr Tiss-mCnt
Synonyms
Cr Tiss-mCnt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

CRP is a marker for inflammation, which can occur due to infections, injuries, or certain medical conditions. High levels may signal an ongoing inflammatory process that your doctor needs to address.

What to Expect Before the Test

No special preparation is needed. You may have blood drawn from a vein in your arm. Tell your doctor about any medications or supplements you’re taking, as some may affect results.

This test is often used to monitor chronic inflammatory conditions, check for infections, or evaluate response to treatments like steroids.

CRP levels may be checked in people with suspected infections (e.g., pneumonia, urinary tract infections), autoimmune diseases (e.g., rheumatoid arthritis), or after surgery to monitor healing.

Results are not always given in absolute numbers, but doctors compare them to your baseline or to others in your condition. Very high or very low levels may prompt further testing or discussions with your provider.

Interpretation depends on your medical history, symptoms, and other test results. For example, elevated CRP may indicate inflammation, while very low levels might suggest suppressed immune response.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

CRP is a useful tool for detecting and tracking inflammation, guiding treatment decisions, and assessing disease activity in conditions like heart disease, arthritis, or sepsis. It helps doctors balance risks of over- or undertreating inflammation.

Short name

CRP Level

Frequently asked questions

What causes CRP levels to change?
CRP levels rise in response to infections, injuries, surgeries, or autoimmune diseases. Stress, certain medications (e.g., steroids), and even some chronic conditions (e.g., heart disease) can also affect CRP. Smoking or obesity may influence baseline levels.
Does CRP always indicate a serious problem?
Not necessarily. Mild elevations may occur with common illnesses like colds or minor infections. Your doctor will consider your symptoms, other tests, and medical history to determine if CRP results are concerning.
Can CRP levels be affected by diet or lifestyle?
Yes, diet, exercise, smoking, and weight can influence CRP levels. Reducing inflammation through diet (e.g., Mediterranean diet), exercise, and avoiding smoking may help lower CRP over time, but results depend on individual health factors.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy