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Cardiolipin Antibody (IgM) – Phospholipid Antibody Test

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of IgM antibodies against cardiolipin, a protein-lipid complex found in cell membranes. These antibodies may be linked to certain autoimmune conditions.

Quick summary

["This test helps assess potential autoimmune or inflammatory conditions, including rare blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30923-7
Short code
Cr ?Tm Ur-mCnc
Synonyms
Cr ?Tm Ur-mCnc
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Cardiolipin antibodies are part of a broader class of phospholipid antibodies that can be detected in the blood. These antibodies may form as part of an immune response to unknown triggers, sometimes associated with autoimmune diseases or other systemic conditions. The test specifically looks for IgM antibodies, which are typically produced in response to recent or ongoing immune activity.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms suggestive of autoimmune disorders, such as unexplained fatigue, joint pain, or signs of blood clotting issues. It may also be used in conjunction with other tests to investigate conditions like lupus, antiphospholipid syndrome, or other connective tissue diseases.

What to Expect Before the Test

No special preparation is usually needed for this test. You may have a simple blood draw, similar to other routine blood tests. If you are on blood-thinning medications or have a history of bleeding disorders, let your healthcare provider know before the test.

What the Results Mean

Results are interpreted by your healthcare provider based on your medical history and symptoms. Elevated levels of cardiolipin antibodies may indicate an autoimmune response, but they are not definitive on their own. Further testing and clinical correlation are required to determine the cause and appropriate treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgM Phospholipid Antibodies

Frequently asked questions

How long does it take to get my test results?
Test results are typically available within 1 to 3 business days, depending on your lab’s processing time. Follow-up with your healthcare provider to discuss the results and any next steps.
Can I eat or drink before this test?
No special diet or fasting is required for this blood test. You can eat and drink normally before your appointment.
What are the possible causes of elevated cardiolipin antibodies?
Elevated cardiolipin antibodies can be linked to autoimmune conditions, infections, or other inflammatory processes. They may also appear in people with no underlying disease. Your healthcare provider will consider your symptoms, medical history, and other test results to determine the cause.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy