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Immunoglobulin Profile (Serum) – Electrophoresis

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins called immunoglobulins (antibodies) in your blood using an electrophoresis method. It helps identify variations in antibody levels that may indicate immune system conditions or other health concerns.

Quick summary

["This test helps diagnose or monitor conditions affecting antibody levels in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2167-5
Short code
Cryoglob SerPl Ql
Synonyms
Cryoglob SerPl Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates blood proteins based on their size and electrical charge. The test detects distinct bands representing immunoglobulins (IgG, IgA, IgM, IgD, and IgE) and other proteins, such as albumin and globulins. These bands help assess the concentration and distribution of these proteins.

Why It’s Done

Doctors may order this test to evaluate immune system function, identify immune disorders (e.g., monoclonal gammopathy), check for infections, or monitor conditions like multiple myeloma, lupus, or rheumatoid arthritis.

Common Conditions Monitored

Abnormal findings may suggest immune deficiencies, autoimmune diseases, or malignancies. For example, elevated IgM could indicate chronic infections, while an unusual band pattern might point to monoclonal gammopathy.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in the arm. The blood is processed to separate serum (liquid part without clotting factors) for analysis. The sample is then sent to a lab for electrophoresis, where it’s applied to a gel and subjected to an electric current to separate proteins.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Ig Profile Electrophoresis

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will discuss findings with you based on your symptoms and medical history.
Can I eat or drink before this test?
No special preparation is needed for this test. However, inform your doctor about any medications or supplements you’re taking, as they may affect results.
What does it mean if my immunoglobulin levels are abnormal?
Abnormal levels may indicate an immune disorder, infection, or other health issue. Your doctor will interpret results in the context of your symptoms and medical history to guide further testing or treatment.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy