Venereal Disease Research Laboratory Test for Cerebrospinal Fluid (VDRL CSF)

Why This Test Is Done

Your doctor may order this test if you have symptoms like headaches, neck stiffness, confusion, or other neurological issues that could indicate an infection in your brain or spinal fluid. It’s also used in certain cases of suspected syphilis or other sexually transmitted infections that have spread beyond the bloodstream.

What to Expect Before the Test

You’ll likely have a small needle inserted into your back to collect cerebrospinal fluid. This is usually done in a hospital or clinic setting. You may feel a brief pinch, but the procedure itself is quick. No special preparation is needed.

What the Test Results Mean

Results can be positive (indicating possible infection) or negative (no infection detected). A positive result may require further testing, like a confirmatory VDRL or a different lab test, to confirm the diagnosis. False positives can occur, so doctors will consider other factors.

Possible Side Effects

After the test, you might have mild soreness or bruising at the injection site. Rarely, you could experience a mild headache or fever. If you experience severe pain, swelling, or signs of infection (like redness or fever), contact your doctor.