Cerebrospinal Fluid Chemistry Profile (Documentation-Based Report)
This test measures various chemical substances in your cerebrospinal fluid (CSF), which surrounds your brain and spinal cord. It helps assess conditions affecting brain function, blood-brain barrier integrity, or metabolic processes in the central nervous system.
["This test provides critical insights into potential neurological or systemic health issues by analyzing fluid chemistry in your brain and spinal cord."]
Key facts at a glance
- LOINC
- 104483-3
- Short code
- CSF chem rpt Doc
- Synonyms
- CSF chem rpt Doc
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What Is Cerebrospinal Fluid (CSF)?
Cerebrospinal fluid (CSF) is a clear, watery fluid that surrounds your brain and spinal cord, acting as a cushion and helping to protect them. It also carries nutrients, removes waste, and maintains chemical balance. When taken through a lumbar puncture (spinal tap), CSF can reveal clues about neurological health, infections, or metabolic disorders.
Why Is This Test Done?
Your doctor may order this test if you have symptoms like headaches, neurological deficits, seizures, or signs of inflammation/infection in the brain or spinal cord. It can also help diagnose conditions such as meningitis, multiple sclerosis, or metabolic disorders like mitochondrial diseases.
What Does the Test Involve?
A small needle is inserted into your lower back to collect CSF. The fluid is then analyzed for a range of chemicals, including proteins, glucose, electrolytes, and other biomarkers. Results are documented in a report rather than a single numeric value, as multiple measurements are reviewed together.
Common Conditions Monitored
This test helps identify issues like abnormal protein levels (e.g., in multiple sclerosis), low glucose (indicating infection or inflammation), or elevated white blood cells (suggesting infection or blood leakage into the CSF). It may also detect metabolic imbalances or toxins.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
CSF Chemistry Report
Frequently asked questions
How long does it take to get results from this test?
What happens if my results are abnormal?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy