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Total Antioxidant Capacity of Serum (or Plasma) – Total Radical Scavenging Activity

Published: August 9, 2026Updated: August 16, 2026

This test measures the overall ability of your blood to neutralize harmful free radicals, which can help protect cells from oxidative stress.

Quick summary

["Your blood’s natural antioxidant defenses may be assessed to identify potential oxidative damage or support overall health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82712-1
Short code
CTA LE ves-L
Synonyms
CTA LE ves-L
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct-angio
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

This test evaluates the combined activity of various antioxidants in your blood, including vitamins (like vitamin C and E), enzymes, and other molecules that help prevent damage from unstable molecules called free radicals. The result reflects your blood’s overall capacity to neutralize these harmful substances.

Why Might You Need This Test?

Doctors may order this test to assess oxidative stress, evaluate chronic conditions like diabetes or heart disease, or monitor responses to treatments that increase oxidative burden (e.g., certain medications or lifestyle factors). It can also help identify early signs of oxidative damage in conditions like aging or metabolic disorders.

What Does a Low or High Result Mean?

A lower-than-expected result might suggest insufficient antioxidant protection, which could be linked to chronic inflammation, poor diet, or certain health conditions. A higher-than-expected result may indicate overcompensation by antioxidants but isn’t always clinically significant without further context.

Common Conditions Monitored With This Test

While not a diagnostic test for specific diseases, it’s sometimes used alongside other blood tests to monitor conditions like cardiovascular disease, diabetes, or neurodegenerative disorders where oxidative stress plays a role.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Antioxidant Level

Frequently asked questions

What causes oxidative stress that might affect this test?
Oxidative stress can arise from poor diet (e.g., high intake of processed foods), smoking, excessive alcohol, chronic infections, or certain medications. Lifestyle factors like exercise, sleep, and stress management can also influence antioxidant levels.
Can antioxidants from supplements affect this test result?
Supplements containing antioxidants (e.g., vitamins C and E) may temporarily alter test results, as they directly contribute to neutralizing free radicals. If you take supplements, your doctor may recommend fasting or timing your test to avoid interference.
Is this test the same as measuring individual antioxidants like vitamin C or E?
No, this test measures the combined effect of multiple antioxidants in your blood, providing a broader picture of your antioxidant defense system rather than focusing on a single nutrient.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy