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Total Antioxidant Capacity of Plasma (measured as ORAC - Oxygen Radical Absorbance Capacity)

Published: August 9, 2026Updated: August 16, 2026

This test measures how effectively your blood plasma fights oxidative stress, which can help protect cells from damage caused by free radicals.

Quick summary

["Your blood’s natural defense against oxidative damage is assessed here."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82710-5
Short code
CTA LE ves-R
Synonyms
CTA LE ves-R
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
20
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct-angio
CPT
85651
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test evaluates the total antioxidant capacity of plasma, which combines multiple antioxidants present in your blood. These include vitamins (like vitamin C and E), enzymes, and other compounds that neutralize harmful free radicals. The ORAC method quantifies the overall ability of these antioxidants to absorb oxygen radicals, reflecting your body’s natural oxidative stress resistance.

Why Might You Need This Test?

This test may be ordered to evaluate overall oxidative health, especially if you have conditions linked to oxidative stress (e.g., chronic inflammation, certain cancers, or metabolic disorders). It can also help assess antioxidant supplementation effectiveness or monitor long-term exposure to oxidative damage.

How Is This Test Performed?

A blood sample is drawn from a vein, typically in your arm. The plasma portion is separated and analyzed using the ORAC assay, which measures its ability to neutralize free radicals over time.

What Does a Low or High Result Mean?

Results reflect the combined strength of your blood’s antioxidants. A lower capacity may indicate higher oxidative stress, while a higher capacity suggests stronger natural defenses. Interpretation depends on clinical context and your overall health.

Reference range

Adult males: 0-15 mm/hr; Females: 0-20 mm/hrN/A

Specimen: serum

No special preparation required. CRP may be affected by acute illness.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Understanding Oxidative Balance

Short name

Plasma Antioxidant Capacity

Frequently asked questions

How often will I need this test?
This test is generally not routine but may be recommended periodically if you have chronic health conditions, take antioxidant supplements, or are at higher risk for oxidative damage. Your healthcare provider will determine the best timing based on your needs.
What do the results of this test typically show in most healthy individuals?
In healthy individuals, results typically indicate a baseline level of antioxidant capacity that balances oxidative stress. However, because reference ranges vary by lab and individual factors, your results will be compared to your own baseline or clinical context rather than a single standard.
Can lifestyle changes affect this test result?
Yes, diet, exercise, smoking status, and exposure to pollutants can influence antioxidant levels. Eating antioxidant-rich foods (e.g., fruits, vegetables, nuts) or avoiding smoking may support higher antioxidant capacity over time.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy