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Auer Rods, Peripheral Blood Smear — Microscopic Identification

Published: August 9, 2026Updated: August 16, 2026

A blood-smear test that looks for Auer rods, needle-shaped inclusions sometimes found inside abnormal white blood cells.

Quick summary

["Detecting Auer rods can support a diagnosis of acute myeloid leukemia, but results must be interpreted with the rest of the blood work."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86962-8
Short code
CTA UE ves-Bl W contr IV
Synonyms
CTA UE ves-Bl W contr IV
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct-angio
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test examines a stained blood smear under a microscope to look for Auer rods. These are needle-shaped packages of cellular material that may be present in certain abnormal white blood cells called myeloblasts.

Why might I need this test?

Auer rods may be checked when a complete blood count or blood-smear review suggests an abnormality involving white blood cells. They can provide important evidence when evaluating possible acute myeloid leukemia or related blood disorders.

How is the test performed?

A blood sample is collected, spread across a slide, and stained. A laboratory professional or hematologist then uses a microscope to examine the white blood cells for Auer rods and other abnormal features.

How do I prepare for the test?

No specific fasting or medication instructions are usually required for a routine peripheral blood smear. Follow any instructions provided by your healthcare professional, particularly if the test is being done as part of a larger evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Auer rods are most strongly associated with acute myeloid leukemia, although they are not found in every case and do not establish the diagnosis by themselves. If they are detected, the result is interpreted with the complete blood count, other laboratory studies, symptoms, and possibly bone marrow testing. Their absence does not rule out acute myeloid leukemia.

Short name

Auer Rods

Frequently asked questions

What are Auer rods?
Auer rods are needle-shaped structures made from packages of proteins and other cellular material. They can form inside abnormal myeloid cells in the bone marrow and circulate in the blood.
Does a positive Auer rod result mean I have leukemia?
It can support suspicion for acute myeloid leukemia, but it is not a stand-alone diagnosis. A hematologist will interpret the finding along with the blood count, additional tests, and your medical history.
Does the test require fasting?
Usually, no. A peripheral blood smear generally requires only a routine blood sample and does not require fasting unless your healthcare professional gives different instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy