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Cholesterol (Total) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of cholesterol in your blood, which is an important part of your overall heart health.

Quick summary

["Your total cholesterol level helps assess your risk for heart disease and other cardiovascular conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
87872-8
Short code
CT Clavicle-R
Synonyms
CT Clavicle-R
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to evaluate your cholesterol levels, monitor existing heart health conditions, or check for risk factors like high cholesterol that could lead to serious health issues over time. It’s often part of a broader cardiovascular screening.

What Does the Result Mean?

While specific reference ranges vary by lab, higher-than-normal cholesterol levels may indicate an increased risk of plaque buildup in your arteries, which can restrict blood flow and raise the risk of heart attack or stroke. Lower-than-normal levels might suggest other health concerns that need further investigation.

How Is the Test Performed?

A blood sample is drawn from a vein, usually in your arm, and sent to a lab. The serum (liquid part of blood after clotting) is analyzed to measure cholesterol concentration using a standardized method.

What Can Affect Results?

Several factors can influence cholesterol levels, including diet (especially saturated and trans fats), physical activity, genetics, certain medications (like cholesterol-lowering drugs), and underlying health conditions like diabetes or thyroid disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Cholesterol plays a critical role in cell membrane structure and hormone production, but excessively high levels can lead to atherosclerosis (plaque buildup in arteries), increasing the risk of heart disease, stroke, or peripheral artery disease. Regular monitoring helps manage risk and guide lifestyle or medical interventions.

Short name

Total Cholesterol

Frequently asked questions

What are the normal cholesterol levels?
There is no single ‘normal’ range for everyone, as it depends on age, sex, and overall health. Your doctor will interpret results in the context of your medical history and other test results.
Could my cholesterol levels be affected by recent meals or medications?
Yes, eating a high-fat meal shortly before your blood draw can temporarily raise cholesterol levels. If you’re on cholesterol-lowering medications, your doctor may recommend fasting before testing to get an accurate result.
Is there anything I should do to prepare for this test?
Typically, no special preparation is needed, but your doctor may advise fasting (not eating or drinking anything except water) for 8–12 hours before the test if it’s part of a lipid panel.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy