Creatinine Clearance (Calculated from Serum Creatinine and Estimated Glomerular Filtration Rate)

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like frequent urination, swelling in your legs, or unexplained fatigue. It’s also used to monitor kidney health in people with diabetes, high blood pressure, or a history of kidney problems. Sometimes, it’s part of routine check-ups for those at higher risk of kidney issues.

What Does the Test Involve?

You’ll have a simple blood draw to measure your serum creatinine level. Additionally, you may need to provide a 24-hour urine sample to measure how much creatinine is excreted over that time. The test combines these results with your age, sex, and weight to calculate your creatinine clearance.

What Are the Results Used For?

The results help determine if your kidneys are working properly. Lower than expected clearance may indicate kidney damage or disease, while higher levels might suggest dehydration or other conditions. This test is often used alongside other kidney function tests to get a full picture.

What Can Affect My Results?

Several factors can influence your creatinine clearance, including dehydration or overhydration, recent exercise, certain medications, or medical conditions like heart disease or liver problems. It’s important to follow any instructions your healthcare provider gives you before the test, such as avoiding certain foods or drinks.