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C-reactive protein (CRP) with high-sensitivity measurement (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein called C-reactive protein (CRP) in your blood. CRP is a marker that helps your body detect inflammation, often used to check for signs of infection, injury, or other conditions causing inflammation.

Quick summary

["hs-CRP helps doctors monitor inflammation levels in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30601-9
Short code
CT Guided Abd Bx
Synonyms
CT Guided Abd Bx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to evaluate whether you have low-grade inflammation—even when you don’t have obvious symptoms. High-sensitivity CRP is particularly useful for assessing risks of heart disease, certain autoimmune conditions, or inflammation-related complications after surgery or trauma.

What Does a High or Low Result Mean?

A higher-than-normal CRP level may indicate ongoing inflammation, which could be linked to infections, autoimmune diseases, or conditions like heart disease. A lower-than-normal level suggests minimal inflammation, but it doesn’t rule out other possible causes of symptoms.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The blood is sent to a lab where it’s analyzed using a sensitive method to detect CRP levels accurately.

What Can Affect Results?

Several factors can influence CRP levels, including recent infections, injuries, stress, certain medications (like steroids), or even physical activity. Smoking, obesity, or chronic conditions like diabetes may also play a role.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

hs-CRP

Frequently asked questions

What does CRP measure?
CRP measures the concentration of a protein produced by your liver in response to inflammation. It’s not specific to any single condition but is a general indicator of your body’s inflammatory state.
How often should I get this test?
Your doctor will determine the frequency based on your health needs. Some people get it yearly to monitor heart health or inflammation risks, while others may need it more often if they have a chronic condition.
Can I eat or drink before this test?
Typically, you can eat and drink normally unless your doctor specifies otherwise. However, fasting may be required for some tests, so always follow your healthcare provider’s instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy