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Adrenal Cortical Tissue Biopsy with Computed Tomography (CT) Guidance

Published: August 9, 2026Updated: August 16, 2026

This test involves a small tissue sample taken from your adrenal glands using imaging guidance to help diagnose conditions like tumors, cysts, or inflammation.

Quick summary

["A guided biopsy helps doctors examine adrenal tissue for potential health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36767-2
Short code
CT Guided Adrenal Bx
Synonyms
CT Guided Adrenal Bx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is an Adrenal Biopsy?

An adrenal biopsy is a procedure where a needle is guided by CT scans to collect a small piece of tissue from your adrenal glands. These glands sit atop your kidneys and produce important hormones like cortisol and aldosterone. The procedure helps diagnose problems such as tumors, cysts, or infections that may not be visible on imaging alone.

Procedure Details

You’ll likely receive local anesthesia to numb the area, and the biopsy may take about 15–30 minutes. Blood loss is minimal, but you may experience mild bruising or soreness afterward. Follow-up imaging or tests may be needed to monitor results.

Preparation and Recovery

Prepare by fasting for 4–6 hours before the procedure if sedation is used. Avoid heavy lifting or strenuous activity for 24 hours. Most people recover within a few days, but check with your doctor if you have concerns about bleeding or infection.

Why Is This Test Done?

Your doctor may recommend this test if you have unexplained adrenal masses, abnormal hormone levels, or symptoms like weight changes, fatigue, or high blood pressure that suggest adrenal dysfunction.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

How long will I need to wait for results?
Results typically take 1–2 weeks to review by a pathologist, who will examine the tissue under a microscope. Your doctor will discuss findings during a follow-up visit.
Will I feel pain during the biopsy?
You may feel mild discomfort during the procedure, but local anesthesia ensures it’s not painful. Sedation can help if you’re anxious. Pain after the procedure is usually mild and managed with over-the-counter pain relievers.
Can I drive myself home after the procedure?
No, you should arrange for someone to drive you home. Avoid driving or operating heavy machinery for 24 hours due to potential drowsiness from anesthesia or sedation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy