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Aspiration Cytology of Bone Marrow with Guided Sampling (Fine Needle Aspiration)

Published: August 9, 2026Updated: August 16, 2026

This test involves collecting a small sample of bone marrow fluid and cells from your bone using a thin needle. It helps doctors examine cells for signs of infection, cancer, or other blood disorders.

Quick summary

["Bone marrow aspiration helps diagnose conditions affecting blood production or detect abnormalities in your cells."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25042-3
Short code
CT Guided Asp or Bx
Synonyms
CT Guided Asp or Bx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Bone Marrow Aspiration Used For?

Doctors may order this test to investigate symptoms like fatigue, unexplained weight loss, frequent infections, or unusual bruising. It’s also used to check for conditions such as leukemia, lymphoma, anemia, or other blood-related disorders before treatments like chemotherapy or bone marrow transplants.

How Is the Procedure Performed?

You’ll likely receive a local anesthetic to numb the area, usually in your hip or upper thigh. A doctor will insert a thin needle into your bone to collect marrow fluid and cells. The procedure usually takes a few minutes and may cause mild discomfort.

What Happens After the Test?

After the procedure, you may feel some soreness or bruising at the site. You’ll need to rest for a short time and avoid heavy lifting or strenuous activity for a day or two. Your doctor will analyze the sample under a microscope to look for abnormal cells or signs of disease.

How Are Results Interpreted?

Results are reviewed by a pathologist, who examines the cells for signs of infection, cancer, or other blood disorders. Normal results mean your marrow appears healthy, while abnormal findings may indicate conditions needing further medical evaluation or treatment.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Bone marrow aspiration is critical for diagnosing hematologic diseases, including cancers like leukemia or multiple myeloma, as well as blood disorders such as thalassemia or sickle cell disease. It may also assess bone marrow function in patients with unexplained anemia or immune deficiencies.

Short name

Bone Marrow Aspiration Cytology

Frequently asked questions

Why might my doctor recommend this test?
Your doctor may suggest bone marrow aspiration if you have symptoms like persistent fatigue, frequent infections, unusual bleeding, or if tests like blood counts or imaging studies raise concerns about blood disorders or cancer.
Will I feel pain during the procedure?
You’ll likely feel mild discomfort or pressure, but a numbing medicine will help reduce pain. Most people describe it as similar to a minor needle prick, though some may feel slight soreness afterward.
How soon will I get my results?
Results are typically available within a few days to a week, depending on the complexity of the analysis. Your doctor will discuss them with you during a follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy