Bone marrow biopsy with deep core needle aspiration (CT-guided)

Why is this test done?

Your doctor may recommend this test if you have symptoms like fatigue, unexplained bruising, frequent infections, or unexplained weight loss. It may also be used to diagnose or monitor conditions such as anemia, leukemia, lymphoma, or bone disorders like osteoporosis or bone metastases.

What happens during the procedure?

You’ll lie on your side or back while a radiologist uses imaging (like CT scans) to guide a needle into your bone, usually in the hip or upper thigh. A small amount of bone marrow and surrounding cells are collected. You may feel pressure or discomfort but should not feel pain. Local anesthesia is often used to numb the area.

What should you expect after the procedure?

You’ll rest for a short time before going home. You may have mild bruising, swelling, or soreness at the site. Avoid heavy lifting or strenuous activity for a few days. Contact your doctor if you experience severe pain, excessive bleeding, or signs of infection (e.g., fever, redness, or pus).

What does the test involve?

The collected sample is examined under a microscope to analyze bone marrow cells, fat cells, and blood-forming elements. Pathologists look for abnormal cells, signs of infection, or other issues that may indicate underlying conditions like blood cancers, genetic disorders, or bone diseases.