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Cerebrospinal Fluid Total Protein by Bromocresol Green (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total protein content in your cerebrospinal fluid (CSF), which is the fluid surrounding your brain and spinal cord. It helps assess conditions affecting the brain’s protective barrier or fluid balance.

Quick summary

["A protein test in your spinal fluid can help diagnose or monitor conditions like infections, inflammation, or structural issues in the brain."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35886-1
Short code
CT Guided Brst PC fluid asp
Synonyms
CT Guided Brst PC fluid asp
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like headaches, neck stiffness, confusion, or neurological problems that suggest an issue with your brain’s fluid or protein levels. It’s also used to check for conditions like meningitis, multiple sclerosis, or tumors.

What to Expect Before the Test

You’ll likely have a spinal tap (lumbar puncture) where a small needle is inserted into your lower back to collect CSF. The procedure takes about 15–30 minutes and may cause mild discomfort. You may be asked to lie on your side or sit for a short time afterward.

What the Results Mean

Results are qualitative (descriptive rather than numerical). High protein levels might indicate inflammation, infection, or blood in the CSF. Low levels could suggest certain brain conditions or blockages. Your provider will interpret results in the context of your symptoms and medical history.

Common Conditions Monitored

This test helps diagnose or track conditions like meningitis, multiple sclerosis, Guillain-Barré syndrome, or brain tumors. It can also rule out issues like bleeding in the brain or certain types of encephalitis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated protein levels in CSF often signal inflammation, immune responses, or breakdown of the blood-brain barrier. Low protein levels may suggest impaired fluid drainage or rare metabolic disorders. Always discuss results with your doctor, as they’re part of a broader evaluation.

Short name

CSF Protein Qualitative Test

Frequently asked questions

How long does it take to get results from this test?
Results are typically available within 1–2 business days, depending on lab processing times. Your provider will contact you once they’re ready for discussion.
What are the most common reasons for this test?
Common reasons include unexplained headaches, neurological symptoms (like weakness or vision changes), suspected meningitis, or monitoring conditions like multiple sclerosis or brain tumors.
Is there anything I should avoid before the test?
Avoid heavy lifting or strenuous activity for 24 hours before the procedure to reduce discomfort. Stay hydrated but avoid caffeine or alcohol before the test, as they may affect fluid balance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy