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CT-Guided Chest Biopsy with Intravenous Contrast

Published: August 9, 2026Updated: August 16, 2026

A CT-guided biopsy uses imaging to guide a needle into a suspicious area in the chest and collect tissue or cells for analysis.

Quick summary

["This test helps determine the cause of a suspicious lung or chest finding by obtaining a sample for laboratory examination."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35909-1
Short code
CT Guided Chest Bx--W contr IV
Synonyms
CT Guided Chest Bx--W contr IV
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A CT-guided chest biopsy is a minimally invasive procedure in which a needle is guided into the lung or another area of the chest using CT images. Intravenous contrast may be given to help identify blood vessels and improve imaging during the procedure.

Why might I need this test?

This test may be recommended to evaluate an unexplained lung nodule, mass, enlarged lymph node, or another suspicious chest finding. The collected sample can be examined for cancer, infection, inflammation, or other tissue abnormalities.

How is the test performed?

You will lie on a CT scanner table, and the imaging team will identify a safe needle path, often using local anesthetic. A biopsy needle is then advanced through the skin to collect tissue or fluid, which is sent to a laboratory for examination.

How do I prepare for the test?

Follow the instructions provided by the imaging center, which may include fasting or withholding certain medicines. Tell the care team about any contrast allergy, kidney disease, bleeding problems, blood-thinning medicines, or possible pregnancy before the procedure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CT-guided chest biopsy with IV contrast

Frequently asked questions

Is a CT-guided chest biopsy a surgical procedure?
No. It is usually a needle biopsy performed through the skin without an incision, although complications such as bleeding or collapsed lung can occur.
Why is intravenous contrast used?
Intravenous contrast can help the CT team distinguish blood vessels from other structures and guide the biopsy more safely. The care team will assess whether contrast is appropriate for you.
When will the biopsy results be available?
Timing can vary because some samples require special laboratory processing. Your clinician will explain when results are expected and how you will receive them.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy