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CT-Guided Chest Biopsy Without Contrast

Published: August 9, 2026Updated: August 16, 2026

A CT-guided procedure that removes a small tissue sample from the chest for examination under a microscope, without using contrast material.

Quick summary

["This image-guided biopsy helps determine the cause of a suspicious chest lesion."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35911-7
Short code
CT Guided Chest Bx--WO contr
Synonyms
CT Guided Chest Bx--WO contr
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A CT-guided chest biopsy is a minimally invasive procedure in which a needle is directed into a suspicious area in the chest using CT images. The collected tissue is examined by a pathologist to identify disease.

Why might I need this test?

This test may be recommended when a lung or other chest lesion cannot be identified confidently from imaging alone. It can help diagnose conditions such as infection, inflammation, or cancer.

How is the test performed?

After local numbing medication is given, a biopsy needle is inserted through the skin and advanced to the target under CT guidance. Several small tissue samples may be removed, and the needle is then withdrawn. The samples are sent to a laboratory for pathologic examination.

How do I prepare for the test?

Follow the instructions provided by the procedure team, including any medication changes. Tell the team about blood-thinning medicines, allergies, pregnancy, or previous reactions to numbing medication. You may need to fast for a period and should arrange transportation if sedation is planned.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CT-guided chest biopsy

Frequently asked questions

Does this procedure use contrast material?
No. The test is performed without iodinated contrast, although CT images are used to guide the needle.
Is a CT-guided chest biopsy painful?
Most patients feel pressure or a brief needle pinch rather than sharp pain because local numbing medication is used. Sedation may be offered depending on the procedure and the patient's condition.
When will I receive the biopsy results?
Timing varies because some samples need special stains or additional tests. The care team will explain when results are expected and will contact you when they are available.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy