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CT-Guided Chest Biopsy Without Intravenous Contrast

Published: August 9, 2026Updated: August 16, 2026

A CT-guided needle biopsy samples a suspicious area in the chest to help identify cancer, infection, inflammation, or another tissue abnormality.

Quick summary

["This procedure uses CT imaging to guide a needle and obtain chest tissue for examination by a pathologist."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35910-9
Short code
CT Guided Chest Bx--WO+W contr IV
Synonyms
CT Guided Chest Bx--WO+W contr IV
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A CT-guided chest biopsy is a minimally invasive procedure in which CT images help the clinician guide a needle into a suspicious area of the chest. Tissue is removed and examined in a laboratory to determine its cause. Intravenous contrast dye is not used for this procedure.

Why might I need this test?

This test may be recommended when imaging shows a lung mass, enlarged lymph node, or another unexplained area in the chest. It can help evaluate whether tissue is cancerous or more likely to represent infection, inflammation, or a benign condition.

How is the test performed?

You will lie on a CT scanner, usually on your side or back. After the area is numbed, a biopsy needle is inserted using CT images for guidance, and several small tissue samples are collected. A bandage is placed over the site, and the samples are sent to a pathologist for examination. Some patients may receive medicine for comfort or anxiety.

How do I prepare for the test?

Follow the instructions provided by the imaging center, including whether to stop any medicines and what to eat or drink beforehand. Blood thinners may need special management, but you should not stop them without instructions from your clinician. Arrange transportation home if you receive sedation, and do not drive until the clinician says it is safe.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CT-guided chest biopsy

Frequently asked questions

Does this test use intravenous contrast dye?
No. CT is used to guide the biopsy, but intravenous contrast dye is not given for this procedure.
Is a CT-guided chest biopsy painful?
The area is usually numbed before the needle is inserted, so you may feel pressure or brief discomfort. Pain medication or mild sedation may be offered depending on the situation.
When will the biopsy results be available?
The timing varies by the laboratory and the tests needed. Your clinician will tell you when to expect the results and how they will be communicated.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy