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Cystatin C - Quantitative Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of cystatin C, a protein produced by all cells in the body. It helps assess kidney function.

Quick summary

["Cystatin C helps evaluate kidney health and may be used alongside other tests to monitor kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42021-6
Short code
CT Guided C-spine Needle loc
Synonyms
CT Guided C-spine Needle loc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check how well your kidneys are working, especially if you have symptoms like fatigue, swelling, or changes in urine output. It can also be used in people with diabetes, high blood pressure, or a family history of kidney disease to monitor progression or guide treatment decisions.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw if instructed by your provider. Bring any medications you’re currently taking to your appointment.

How the Test Is Performed

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but it usually doesn’t cause discomfort. The blood sample is then sent to a lab for analysis.

What the Results Mean

Higher than expected levels of cystatin C may indicate reduced kidney function, while lower levels might suggest overhydration or other conditions. Your results will be interpreted by your provider in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Cystatin C is a reliable marker for kidney function because it’s produced by all cells and doesn’t depend on liver function or hydration status like other kidney tests. It’s often used alongside creatinine levels to better assess kidney health, especially in people with diabetes or those who have limited kidney function due to other conditions.

Short name

Cystatin C

Frequently asked questions

How long does it take to get my results?
Results from this test are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
Unless instructed otherwise by your provider, you may eat and drink normally before this test. Some tests may require fasting, but cystatin C levels are not affected by food or hydration status.
Is there anything I should avoid before the blood draw?
Avoid excessive physical activity or stress before the blood draw, as these can sometimes affect blood pressure or heart rate. If you’re on blood thinners or have a history of bleeding disorders, let your provider know before the test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy