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Guided Fine-Needle Aspiration Cytology (CSF) for Cytologic Examination

Published: August 9, 2026Updated: August 16, 2026

This test involves collecting a small sample of cerebrospinal fluid (CSF) using a fine needle to examine cells under a microscope. It helps identify abnormal cells that may suggest conditions like infections, tumors, or inflammatory diseases in the brain and spinal cord.

Quick summary

["A key test for diagnosing neurological conditions by analyzing cell samples from CSF."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30580-5
Short code
CT Guided FNA
Synonyms
CT Guided FNA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
136
Ref high
145
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
CPT
84295
SNOMED
110741000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is the Purpose of This Test?

This test is typically performed when doctors suspect conditions such as brain tumors, infections (like meningitis), or other neurological disorders. It helps determine the presence of abnormal cells that may not be visible through standard imaging or blood tests alone.

How Is the Sample Collected?

A healthcare provider will insert a thin needle into the spinal column to collect a small amount of CSF. You may feel pressure or discomfort, but it usually doesn’t cause pain. The sample is then sent to the lab for microscopic examination.

What Can This Test Detect?

The test can detect abnormal cells, such as cancer cells, bacteria, or inflammatory markers. For example, it may identify leukemia cells in the CSF, signs of meningitis, or other neurological abnormalities that require further medical evaluation.

How Are Results Interpreted?

Results are reviewed by a pathologist, who examines the cells under a microscope. Abnormal findings may include clusters of cancer cells, signs of infection, or other markers that guide further medical decisions, such as additional treatments or diagnostic tests.

Reference range

Adult: 136-145 mmol/LN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a critical role in diagnosing neurological diseases by providing direct evidence of abnormal cells in the CSF. It helps doctors determine the exact cause of symptoms like headaches, neurological deficits, or unexplained spinal fluid changes, guiding personalized treatment plans.

Short name

CSF FNA Cytology

Frequently asked questions

Why might my doctor recommend this test?
Your doctor may recommend this test if you have symptoms like persistent headaches, neurological symptoms (such as weakness, numbness, or vision changes), or if they suspect a condition like meningitis, brain tumor, or other spinal abnormalities.
What are the possible risks or side effects of this procedure?
The procedure is generally safe, but possible risks include mild headaches, dizziness, or a small risk of infection at the injection site. Rarely, more serious complications like bleeding or nerve damage may occur, but these are uncommon.
How long will it take to get results from this test?
Results are typically available within 1–3 business days, depending on lab processing times. Your doctor will discuss the findings with you during a follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy