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CT-Guided Stereotactic Head Biopsy with Intravenous Contrast

Published: August 9, 2026Updated: August 17, 2026

A minimally invasive procedure in which CT imaging guides a needle into a targeted area of the head to obtain tissue for diagnosis.

Quick summary

["This procedure obtains a small sample of tissue from a specific head lesion so a pathologist can determine what it is."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
24585-2
Short code
CT Guided Head Str Bx--W contr IV
Synonyms
CT Guided Head Str Bx--W contr IV
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
135
Ref high
980
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
CPT
82626
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A CT-guided stereotactic head biopsy is a procedure that uses computed tomography images to help position a biopsy needle at a specific target within the head. A small sample of tissue is removed for examination by a pathologist. Intravenous contrast may be used to improve the visibility of brain structures and blood vessels during the procedure.

Why might I need this test?

This procedure may be recommended when imaging has identified an abnormal area that could represent a tumor, infection, inflammation, or another condition. Examining the tissue directly may help establish a diagnosis when imaging and other tests are not conclusive.

How is the test performed?

After the target is identified with CT imaging, a thin needle is carefully advanced to the area. A small tissue sample is collected, and the needle is removed. The procedure is usually performed with local anesthesia and sedation, depending on the clinical situation and the institution's protocol.

How do I prepare for the test?

Your care team will provide specific instructions. These may include reviewing medications, allergies, kidney function, blood-thinning medicines, pregnancy status, and imaging studies. Follow the team's instructions about fasting, medicines, transportation, and post-procedure care.

Reference range

NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

The biopsy may identify the type of cells present in a targeted abnormality, such as a tumor or inflammatory process. Results can guide treatment planning, but the tissue findings must be interpreted together with imaging, symptoms, the physical examination, and other laboratory studies. If no conclusive diagnosis is possible, additional testing or another tissue sample may be needed.

Short name

CT-guided stereotactic head biopsy

Frequently asked questions

Is a CT-guided stereotactic head biopsy the same as a surgical biopsy?
Not exactly. It is a needle-based procedure that removes a small amount of tissue through a burr hole rather than an open operation. The approach is designed to obtain diagnostic tissue with as little disruption as possible.
Why is contrast used during the procedure?
Intravenous contrast can help outline brain structures and blood vessels on CT images. This may improve planning and guidance when positioning the biopsy needle.
How soon are the biopsy results available?
Timing varies. Some preliminary information may be available during the procedure, while a complete pathology report can take several days or longer, particularly if specialized testing is needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy