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CT-Guided Stereotactic Biopsy of the Head Without Contrast

Published: August 9, 2026Updated: August 17, 2026

A minimally invasive procedure that uses CT imaging to guide a needle biopsy of a suspicious area in the head, without contrast.

Quick summary

["This test obtains tissue from a suspicious area in the head using CT guidance and no contrast."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
36929-8
Short code
CT Guided Head Str Bx--WO contr
Synonyms
CT Guided Head Str Bx--WO contr
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
135
Ref high
980
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
CPT
82626
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A CT-guided stereotactic biopsy is a procedure in which a needle is guided into a specific area of the head to remove tissue for examination. CT images help the clinician target the exact location, and no contrast is used during the procedure.

Why might I need this test?

This test may be recommended when imaging shows a suspicious mass, lesion, or abnormal tissue in the head and the cause cannot be determined from scans alone. The tissue sample can help identify infection, inflammation, an autoimmune condition, or a benign or cancerous growth.

How is the test performed?

After local numbing medicine is given, the patient may receive sedation depending on the procedure and clinical situation. Using CT guidance, the clinician positions a biopsy needle through the skull or through a small opening and removes one or more small samples of tissue. The samples are then examined in a laboratory.

How do I prepare for the test?

The care team will provide specific instructions, including which medicines to stop or adjust and when to stop eating or drinking. Tell the clinician about allergies, bleeding problems, blood thinners, pregnancy, implanted devices, and any previous reactions to sedation or anesthesia.

Reference range

NCBI: DHEA-S Male 135-980 µg/dL; Female 30-260 µg/dLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CT-guided head biopsy

Frequently asked questions

Is this test the same as a brain biopsy?
It is a type of image-guided biopsy of a suspicious area in the head. The exact target may be in the brain or nearby tissues, depending on the clinical situation.
Will I be awake during the biopsy?
Local numbing medicine is used, and sedation or anesthesia may also be given. The care team will explain what to expect based on the planned procedure and your overall health.
How long does it take to get the biopsy results?
Timing varies because some samples need special laboratory processing. The clinician will provide an estimated timeframe and explain the results when they are available.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy