Hemoglobin A1c (HbA1c) with 24-hour urine collection for total urinary excretion of hemoglobin-derived compounds (e.g., methemoglobin, bilirubin metabolites)
This test measures the total amount of hemoglobin-related substances excreted in your urine over 24 hours. It helps assess how much hemoglobin (the oxygen-carrying protein in red blood cells) is broken down and processed in your body.
["This test may help evaluate conditions affecting red blood cell breakdown or kidney function."]
Key facts at a glance
- LOINC
- 42136-2
- Short code
- CT Guided Hrt Bx
- Synonyms
- CT Guided Hrt Bx
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ct
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test looks at compounds derived from hemoglobin, such as methemoglobin and bilirubin metabolites, that appear in urine after red blood cells are broken down. These compounds are tracked over a full day to get a comprehensive picture of hemoglobin metabolism.
Why It Might Be Ordered
Your healthcare provider may order this test if you have symptoms or conditions that could affect how your body processes hemoglobin, such as hemolytic anemia, kidney disease, or certain medications that alter red blood cell breakdown.
How the Test Works
You’ll collect all urine for a 24-hour period in a special container. The sample is then analyzed to measure the total amount of hemoglobin-derived substances excreted.
What to Expect Before the Test
No special preparation is needed beyond collecting urine for the full 24-hour period. Drink plenty of water to help your kidneys filter urine properly, but avoid excessive diuretics or medications that might affect urine output.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
HbA1c Urine Total Excretion
Frequently asked questions
How does this test differ from a standard HbA1c blood test?
Can I take medications before collecting urine for this test?
What if I miss collecting urine for part of the 24-hour period?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy