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CT-Guided Kidney Biopsy Without Intravenous Contrast

Published: August 9, 2026Updated: August 16, 2026

A CT-guided biopsy that removes a small sample of kidney tissue for examination under a microscope, without injecting intravenous contrast.

Quick summary

["This procedure provides kidney tissue for diagnosis when imaging and urine or blood tests have not identified the cause of a kidney problem."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
89614-2
Short code
CT Guided Kidney Bx--WO contr
Synonyms
CT Guided Kidney Bx--WO contr
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A CT-guided kidney biopsy is a minimally invasive procedure in which a needle is guided into a kidney using CT images. A small piece of tissue is removed and examined by a pathologist to identify the cause of certain kidney problems.

Why might I need this test?

This biopsy may be recommended when kidney function is abnormal or unexplained, or when imaging suggests a kidney condition. It can help diagnose problems involving kidney tissue, including some forms of inflammation, infection, scarring, or other disease.

How is the test performed?

You usually lie on a procedure table, and the area around the biopsy site is numbed with local anesthetic. Using CT guidance, the clinician positions a biopsy needle through the skin into the kidney and removes small samples of tissue. The samples are then sent for laboratory examination.

How do I prepare for the test?

Your care team will provide specific instructions, which may include blood tests, medication review, and fasting if required. You should tell the clinician about blood-thinning medicines, bleeding disorders, kidney function problems, allergies, and any prior imaging contrast reactions before the procedure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Biopsy results may identify or clarify the type of kidney disease and guide treatment or further evaluation. The findings are interpreted together with your symptoms, examination, laboratory results, and imaging, because a small tissue sample does not always represent the entire kidney.

Short name

CT-guided kidney biopsy

Frequently asked questions

Does this procedure use contrast dye?
No intravenous contrast is used during the biopsy, although your care team may determine whether contrast is needed for other imaging performed during the visit.
Is a CT-guided kidney biopsy painful?
The area is numbed with local anesthetic, so most patients feel pressure rather than sharp pain during the biopsy. Some soreness or bruising near the needle site can occur afterward.
What are the main risks?
Potential risks include bleeding, bruising, infection, pain, and rarely injury to nearby organs or blood vessels. Your clinician will review your individual risks and explain how they will be monitored and managed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy