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Nephrology-guided kidney function profile with 24-hour urine collection

Published: August 9, 2026Updated: August 16, 2026

This test evaluates how well your kidneys filter waste and balance fluids over a full day by analyzing urine and blood markers.

Quick summary

["Assesses kidney health and fluid balance through urine and blood measurements over 24 hours."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36772-2
Short code
CT Guided Kidney NT place
Synonyms
CT Guided Kidney NT place
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test includes measurements of electrolytes (like sodium and potassium), creatinine clearance—a key indicator of kidney function—and other substances that help assess how well your kidneys are processing waste and fluids. It also evaluates urine volume and concentration, which can reveal imbalances or kidney-related conditions.

Why It’s Done

Your doctor may order this test if you have symptoms like swelling, frequent urination, fatigue, or if they suspect kidney disease, fluid overload, or electrolyte imbalances. It’s also used to monitor chronic conditions like diabetes or heart failure.

Sample Collection Process

You’ll collect all urine for 24 hours in a special container, starting and ending with your first morning urine. Blood may also be drawn to measure certain markers. Follow your healthcare provider’s instructions precisely to ensure accurate results.

Common Conditions Monitored

This test helps diagnose or manage conditions like chronic kidney disease, kidney stones, fluid retention, or electrolyte disorders. It can also assess how well medications are affecting kidney function.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Elevated creatinine clearance or abnormal urine electrolytes may indicate kidney dysfunction, dehydration, or overhydration. Low urine volume or high sodium/potassium levels could signal kidney disease or other metabolic issues. Results guide treatment adjustments for conditions like heart failure or diabetes.

Short name

Kidney Function Profile (24-hour urine)

Frequently asked questions

How long will I need to collect urine for this test?
You’ll need to collect all urine for a full 24-hour period, starting with your first morning urine and ending with the urine you produce the next morning. This ensures a complete picture of your kidney function and fluid balance.
What if I miss a urine sample or have an accident?
If you miss any urine or experience an accident, notify your lab or healthcare provider immediately. They may need to adjust your test plan or reschedule if the sample isn’t complete.
Can I take medications or eat normally during urine collection?
Follow your doctor’s instructions regarding medications or dietary restrictions. Some medications or foods may affect urine composition, so avoid them unless advised otherwise.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy