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Cystatin C-Based Glomerular Filtration Rate (GFR) with Liver Function Confirmation

Published: August 9, 2026Updated: August 16, 2026

This test measures how well your kidneys filter blood using a protein called cystatin C, along with liver function tests to check how your liver processes certain substances.

Quick summary

["Helps assess kidney function and liver health together in one evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24813-8
Short code
CT Guided Liver CN Bx
Synonyms
CT Guided Liver CN Bx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms of kidney problems (like fatigue, swelling, or frequent urination) or if you have liver issues (like jaundice, itching, or abdominal pain). It’s also used to monitor kidney disease progression or liver conditions that affect kidney function, such as chronic liver disease.

What to Expect Before the Test

No special preparation is needed. You’ll provide a small blood sample, usually drawn from your arm. If a urine sample is involved, you may be asked to collect it at home or in the lab. Avoid heavy meals before the test if instructed by your provider.

How the Test Works

The blood sample is tested for cystatin C, a protein that reflects kidney function. Liver function tests may include checking levels of enzymes or substances that indicate liver health. The results help determine how well your kidneys filter waste and how your liver processes toxins.

What the Results Mean

Results show your estimated glomerular filtration rate (GFR) based on cystatin C levels, along with liver test results. Lower GFR values suggest impaired kidney function, while abnormal liver test results may indicate liver damage or disease. Your doctor will interpret these results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Why This Test Matters

Short name

GFR (Cystatin C) with Liver Test

Frequently asked questions

How often should I get this test?
The frequency depends on your health condition. If you have kidney or liver disease, your doctor may recommend regular monitoring to track changes in your condition. For healthy individuals, this test may not be routine unless you have risk factors (e.g., family history of kidney disease, diabetes, or liver disease).
What do my results mean if they’re outside the normal range?
If your GFR is low, it may indicate kidney problems that could worsen over time. If liver tests are abnormal, it could signal liver damage or inflammation. Your doctor will discuss these findings with you and may recommend further tests or treatments based on your results.
Can I eat or drink anything before this test?
Typically, no special diet or fasting is required unless your doctor specifies otherwise. Follow any instructions they provide, such as avoiding certain medications or foods, to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy