Skip to content

: CT-Guided Fine-Needle Aspiration of the Mediastinum

Published: August 9, 2026Updated: August 16, 2026

: A CT-guided fine-needle aspiration of the mediastinum is a minimally invasive procedure that uses computed tomography (CT) imaging to guide a thin needle into the central chest (mediastinum) to collect a small sample of tissue or fluid for laboratory examination.

Quick summary

[": This procedure helps doctors sample and evaluate abnormal masses or lymph nodes in the mediastinum without requiring open surgery."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44104-8
Short code
CT Guided Mediastinum FNA
Synonyms
CT Guided Mediastinum FNA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
120 N/A – 160 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What the Procedure Is

: During the procedure, you lie on a CT scanning table while images of your chest guide the doctor to the precise location of the abnormal area. A thin needle is passed through the skin of the chest into the mediastinum, and a small sample of cells or fluid is withdrawn. The sample is then sent to a laboratory where a pathologist examines it under a microscope.

: Why It Is Done

: The mediastinum is the space in the center of the chest between the lungs, containing the heart, major blood vessels, lymph nodes, and other structures. When imaging tests reveal an enlarged lymph node, mass, or fluid collection in this area, a tissue sample is often needed to determine whether the finding is benign, infectious, or cancerous. This procedure provides that sample with less trauma than surgical biopsy.

: How to Prepare

: Your care team will give you specific instructions before the procedure. You may be asked to avoid eating or drinking for several hours beforehand and to temporarily stop certain blood-thinning medications. Tell your doctor about any allergies, especially to contrast dye or numbing medication, and about all medicines and supplements you take.

: What to Expect

: The skin is numbed with a local anesthetic, and you may also receive sedation to help you relax. You will need to lie still while the CT images are taken and the needle is inserted; you may be asked to hold your breath briefly at certain points. Afterward, you will be observed for a short time to check for any problems, and you can usually go home the same day.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

: CT-Guided Mediastinal FNA

Frequently asked questions

: Is the procedure painful?
: You will receive a local anesthetic to numb the skin, and sedation may be offered to help you relax. Most people feel only mild discomfort or pressure during the needle insertion. Tell your care team if you feel pain so they can help keep you comfortable.
: What are the risks or complications?
: This is generally a safe procedure, but as with any needle biopsy there is a small risk of bleeding, infection, or a collapsed lung (pneumothorax). Your care team monitors you afterward for these problems. Contact your doctor promptly if you develop worsening chest pain, shortness of breath, fever, or bleeding after the procedure.
: How long until results are available?
: Some preliminary information may be available soon after the procedure, but full laboratory analysis, including any additional testing such as cultures or special stains, can take several days. Your doctor will discuss the results with you and explain what they mean for your care.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy