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C-reactive protein (CRP) measured by high-sensitivity nephelometry

Published: August 9, 2026Updated: August 16, 2026

This blood test measures a protein called C-reactive protein, which your body produces in response to inflammation. It helps assess low-level inflammation that may not be visible with other tests.

Quick summary

["High-sensitivity CRP helps track subtle inflammation, often used alongside other tests for conditions like heart disease or autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
79072-5
Short code
CT Guided RT
Synonyms
CT Guided RT
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a high-sensitivity CRP test to monitor chronic inflammation, evaluate risk for heart disease, or check for signs of conditions like rheumatoid arthritis or other autoimmune diseases. It’s sometimes used in combination with other tests to get a clearer picture of your health.

What Does the Test Involve?

You’ll have a small needle inserted into your arm to draw a small amount of blood. The blood is then sent to a lab where it’s analyzed using a special technique called nephelometry to measure CRP levels precisely.

What to Expect Before the Test

No special preparation is needed, but you may want to avoid heavy meals or strenuous activity 1–2 hours before the test. Let your healthcare provider know if you’re on blood thinners or have any allergies.

What to Expect After the Test

You may feel slight discomfort or bruising at the injection site, but this usually goes away quickly. Apply gentle pressure to the area to help reduce any swelling or bleeding.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

High-sensitivity CRP (hs-CRP)

Frequently asked questions

What does a high or low CRP level mean?
A high CRP level suggests increased inflammation in your body, which could be due to infections, injuries, autoimmune diseases, or other health conditions. A low CRP level usually means your body is not experiencing significant inflammation, but this can vary depending on your overall health and medical history.
How often should I get this test?
The frequency of this test depends on your healthcare provider’s recommendations. Some people may need it yearly or more often if they have a history of chronic inflammation, heart disease, or other conditions that require monitoring.
Can lifestyle changes affect CRP levels?
Yes, lifestyle factors like diet, exercise, smoking, and stress can influence CRP levels. Eating a heart-healthy diet, staying active, quitting smoking, and managing stress may help lower inflammation and CRP levels over time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy