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Soft Tissue Deep Biopsy (Computed Tomography-Guided)

Published: August 9, 2026Updated: August 16, 2026

This procedure involves removing a small sample of tissue from deeper layers of your body using a needle guided by a CT scan to help diagnose conditions like tumors, infections, or inflammatory diseases.

Quick summary

["A CT-guided deep tissue biopsy helps doctors identify abnormalities in soft tissues that may not be visible on standard imaging alone."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90315-3
Short code
CT Guided Soft tiss Deep Bx
Synonyms
CT Guided Soft tiss Deep Bx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may recommend this test if they suspect a condition such as a tumor, infection, or chronic inflammation in deep soft tissues (e.g., muscles, fat, or connective tissue). Common reasons include unexplained lumps, persistent pain, or abnormal findings on imaging studies like MRI or ultrasound.

How the Procedure Works

You’ll lie on your side or back while a CT scanner takes real-time images of the targeted area. A radiologist guides a needle through your skin and into the tissue using the CT scan for precision. A small sample of tissue is collected, which is then sent to a lab for analysis.

Preparation

You may be asked to fast for a few hours before the procedure, depending on your doctor’s instructions. Wear comfortable clothing and remove any jewelry or devices that could interfere with imaging. Inform your doctor about any medications you’re taking, especially blood thinners.

During the Procedure

You’ll receive local anesthesia to numb the area, so you may feel pressure but minimal pain. The procedure typically takes 30–60 minutes. You’ll be monitored closely for any reactions to anesthesia or complications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This biopsy provides critical information for diagnosing conditions like malignant tumors (cancer), benign growths, infections (e.g., abscesses), or autoimmune-related tissue changes. Results help guide treatment plans, such as surgery, further imaging, or targeted therapies.

Short name

CT-Guided Deep Soft Tissue Biopsy

Frequently asked questions

What to Expect After the Procedure
You may experience mild bruising, swelling, or soreness at the biopsy site, which usually improves within a few days. Avoid strenuous activities for 24–48 hours. Follow your doctor’s instructions for wound care and return if you develop signs of infection (e.g., fever, increasing pain).
Will I Need to Stay in the Hospital?
Most people can go home the same day unless you have severe bleeding, infection risk, or other complications. Your doctor will determine if inpatient care is needed based on your health and the procedure’s complexity.
How Long Will Results Take?
Lab results from the tissue sample may take 3–10 business days, depending on the complexity of analysis. Your doctor will contact you once results are available to discuss findings and next steps.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy