Hemoglobin A1c (HbA1c) with 24-hour urine collection for total 24-hour urinary excretion of free cortisol
This test measures your average blood sugar levels over the past 2–3 months and checks how much cortisol you excrete in a 24-hour urine sample.
["Helps track long-term blood sugar control and assess cortisol balance in your urine."]
Key facts at a glance
- LOINC
- 77448-9
- Short code
- CT Hind+Mid ft
- Synonyms
- CT Hind+Mid ft
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ct
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters for Blood Sugar Control
HbA1c reflects the percentage of your red blood cells coated with hemoglobin that has been linked to glucose over time. It’s a key indicator of how well your diabetes or prediabetes is managed, giving a snapshot of your average blood sugar levels over months rather than just recent days.
How HbA1c Works in Your Body
HbA1c forms when glucose attaches to hemoglobin in your red blood cells. Since red blood cells live for about 3 months, this test provides a long-term view of your blood sugar trends, which can help prevent complications like nerve damage or heart disease.
Understanding Cortisol in Urine
Cortisol is a stress hormone produced by your adrenal glands. Measuring its excretion in urine helps assess how your body handles stress and hormone regulation, which can be important for conditions like Cushing’s syndrome or adrenal dysfunction.
What to Expect Before the Test
For the HbA1c, no special preparation is needed. For the 24-hour urine cortisol test, you’ll collect all urine for a full day, starting and ending at the same time each day. Drink plenty of water but avoid caffeine or medications that affect cortisol levels before testing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: HbA1c and Cortisol Together
Short name
HbA1c + 24h Urinary Free Cortisol
Frequently asked questions
What does an abnormal HbA1c or cortisol level mean?
How often should I get this test?
Can diet or lifestyle changes affect these test results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy