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C-reactive protein (CRP) concentration, serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein in your blood, a protein produced by your liver in response to inflammation.

Quick summary

["CRP helps your doctor assess inflammation in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
35957-0
Short code
CT IAC-L
Synonyms
CT IAC-L
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
98
Ref high
107
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ct
CPT
82435
SNOMED
110743000
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may order a CRP test to check for signs of inflammation, monitor conditions like infections, autoimmune diseases, or heart disease, or evaluate how well you’re responding to treatment for these conditions. It can also be used to screen for certain health risks or to monitor chronic conditions over time.

How the Test Works

A small blood sample is taken from a vein in your arm. The blood is then sent to a lab, where it’s analyzed to measure the amount of CRP present. CRP levels are compared to a reference range to determine if they’re within normal limits or if further action is needed.

What to Expect Before the Test

You can eat and drink normally before the test, as it doesn’t require fasting. Wear comfortable clothing with an easy-to-reach sleeve if you’re having the blood drawn. If you’re on blood-thinning medication or have a bleeding disorder, let your doctor know beforehand.

What to Expect During the Test

The blood draw is quick and usually painless. You may feel a slight pinch or sting when the needle is inserted, but most people tolerate it well. Afterward, you might experience a small bruise or swelling at the site, which usually goes away within a day or two.

Reference range

Adult: 98-107 mmol/LN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP

Frequently asked questions

What are the normal CRP levels?
CRP levels vary depending on your health status. Low levels (often below 1 mg/L) may indicate no significant inflammation. Higher levels (above 3–10 mg/L) can signal inflammation, infections, or other health issues. Your doctor will interpret the results in the context of your overall health and medical history.
Can CRP levels change over time?
Yes, CRP levels can fluctuate. They may rise quickly in response to infections, injuries, or illnesses and then return to normal once the body heals. Chronic conditions like arthritis or heart disease may also cause consistently elevated CRP levels.
Does diet or lifestyle affect CRP levels?
Yes, lifestyle factors such as smoking, poor diet, lack of exercise, and obesity can increase CRP levels. Making healthy lifestyle changes, such as eating a balanced diet, exercising regularly, and quitting smoking, may help lower CRP levels and reduce inflammation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy