Creatinine Clearance (24-hour urine collection)
This test measures how well your kidneys filter waste products from your blood over a full day. It helps assess kidney function and how well your kidneys are working to remove waste.
["A 24-hour urine creatinine clearance test helps doctors check kidney health and diagnose kidney disease early."]
Key facts at a glance
- LOINC
- 43767-3
- Short code
- CT Kdny-Bl
- Synonyms
- CT Kdny-Bl
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ct
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Your kidneys play a vital role in filtering waste and excess substances from your blood. This test specifically looks at how efficiently your kidneys clear creatinine, a waste product from muscle metabolism, over a 24-hour period. It provides a more accurate picture of kidney function than a single blood test alone.
How the Test Works
You’ll collect all your urine for a full day, typically starting after waking up the morning of the test. The urine is then sent to the lab for analysis. The lab measures creatinine levels in both your urine and blood (if collected) to calculate your creatinine clearance rate.
What to Expect
You’ll receive clear instructions on when and how to collect your urine samples. It’s important to follow these instructions precisely to ensure accurate results. You may need to wear a special collection bag or use a container to catch all urine for the day.
Factors That Can Affect Results
Several factors can influence your creatinine clearance, including muscle mass, hydration status, diet (especially protein intake), and certain medications. It’s important to discuss any changes in your health, diet, or medications with your healthcare provider before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
24h CrCl
Frequently asked questions
What does a low creatinine clearance mean?
What does a high creatinine clearance mean?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy